78589-59-0

Basic information

• Product Name: 3-(2-Acetoxy-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid methyl ester
• Synonyms: 3-(2-Acetoxy-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid methyl ester
• CAS NO: 78589-59-0
• Molecular Weight: 496.499
• Mol File: 78589-59-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-Acetoxy-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Acetoxy-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid methyl ester(78589-59-0)
• EPA Substance Registry System: 3-(2-Acetoxy-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid methyl ester(78589-59-0)

Safety Data

• Hazardous Substances Data: 78589-59-0(Hazardous Substances Data)

Upstream product

• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 5538-51-2 O-acetylsalicyloyl chloride 

Downstream Products

• 51751-33-8 methyl 2-methylchromone-3-carboxylate 
• 2555-37-5 3-acetyl-4-hydroxychromen-2-one 

Relevant articles and documents

NOUVEAU MODE DE CYCLYSATION DE CETO-YLURES. APPLICATION A UNE SYNTHESE IGINALE D'ACYL-3 HYDROXY-4-COUMARINES ET DE L'HYDROXY-11 BENZO-(b) 12 XANTHONE-12

The thermal decomposition of keto-ylides resulting from the reaction of m- and p-acetoxy benzoyl chlorides with Ph3P=CH-COOMe leads, after saponification to m- and p-phenylpropiolic acid respectively.Ortho substitution by an acyl group generally changes the orientation of the reaction.Thus o-acetoxy-, benzoyloxy- or phenylacetoxy benzoyl chlorides respectively afford: and (R=Me,Ph) in satisfactory yields.Saponification of the first and second ones gives: (R=Me, Ph).This constitutes a new, convenient route to 3-acyl 4-hydroxy cumarins and 11-hydroxy 12H-benzoxanthene 12-one.Formation of these last products involves the carbonyl of the acyloxy-substituent and not of the acyl chloride as previously observed in these series.