78593-33-6 Usage
General Description
3-bromocinnoline is an organic compound with the chemical formula C9H6BrN. It is a brominated derivative of cinnoline, containing a bromine atom attached to the third position of the cinnoline ring. 3-bromocinnoline is a light yellow solid that is insoluble in water but soluble in organic solvents. It is used as a building block in organic synthesis and chemical reactions due to its unique structure and reactivity. 3-bromocinnoline is also used in the pharmaceutical industry for the synthesis of various drugs and as a reagent in research laboratories. Its properties and potential applications make 3-bromocinnoline an important and versatile chemical compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 78593-33-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,5,9 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78593-33:
(7*7)+(6*8)+(5*5)+(4*9)+(3*3)+(2*3)+(1*3)=176
176 % 10 = 6
So 78593-33-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2/c9-8-5-6-3-1-2-4-7(6)10-11-8/h1-5H
78593-33-6Relevant articles and documents
TMP-magnesium and TMP-Zinc bases for the regioselective metalation of the cinnoline scaffold
Klatt, Thomas,Roman, Daniela Sustac,Leon, Thierry,Knochel, Paul
supporting information, p. 1232 - 1235 (2014/03/21)
A regioselective functionalization of cinnolines in positions 3 and 8 using metalations has been developed. This involves either the use of a frustrated Lewis pair consisting of BF3·Et2O and TMP 2Mg·2LiCl or the in situ generated base TMP 2Zn·2MgCl2·2LiCl. Successive metalations allow the preparation of 3,8-disubstituted cinnolines. Various functionalizations by acylation, allylation, and cross-coupling reactions with aryl halides or alkenyl iodides were carried out successfully.
