335242-55-2

Upstream product

• 58585-01-6 1-(2-amino-phenyl)-2-bromo-ethanone 
• 18514-84-6 4(1H)-cinnolon 

Downstream Products

• 80334-78-7 3-bromo-4-chloro-cinnoline 
• 4320-54-1 1-benzyl-3-bromo-1H-cinnolin-4-one 
• 78593-33-6 3-bromocinnoline 
• 78593-34-7 3-bromo-4-phenoxy-cinnoline 
• 82452-98-0 3-iodo-4(1H)-cinnolinone 
• 1246779-55-4 3-[2-Fluoro-3-(trifluoromethyl)phenyl]-1-[3-(methylthio)propyl]cinnolin-4(1H)-one 
• 1246779-83-8 1-(3-chloropropyl)-3-[2-fluoro-(3-trifluoromethyl)phenyl]cinnolin-4(1H)-one 

Relevant academic research and scientific papers

SUBSTITUTED 1-ALKYLCINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION OF SAME

The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from —S-Alk, —SO-Alk, —SO2-Alk, —CO—N(R4)-Alk, —N(R4)SO2-Alk, —N(R4)CO-Alk, —N(R4)SO2—N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.

NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION

The present invention relates to compounds of f formula (I) as cannabinoid receptor modulators, in particular cannabinoid 1 (CB1) or cannabinoid 2 (CB2 ) receptor modulators, and uses thereof f or treating diseases, conditions and/or disorders modulated by a cannabinoid receptor ( such as pain, neurodegenrative disorders, eating disorders, weight loss or control, and obesity).