786-29-8Relevant academic research and scientific papers
An efficient catalyst for PD-catalyzed carbonylation of aryl arenesulfonates
Cai, Chaoxian,Rivera, Nelo R.,Balsells, Jaume,Sidler, Rick R.,McWilliams, J. Christopher,Shultz, C. Scott,Sun, Yongkui
, p. 5161 - 5164 (2006)
(Chemical Equation Presented) Aryl carboxylic esters were synthesized by Pd-catalyzed carbonylation of aryl p-fluorobenzenesulfonates or -tosylates. A unique Josiphos ligand was discovered through high-throughput catalyst screening, which was the key for the successful carbonylation of various substrates. This catalyst is effective and works well for both electron-rich and electron-poor aryl arenesulfonates. Isolated yields of up to 90% were obtained for aryl p-fluorobenzenesulfonates and -tosylates.
