786-87-8Relevant academic research and scientific papers
Synthesis of 2-Chloro-6,11(5H)-morphanthridinedione and Its Rearrangement to 1-Amino-4-hydroxyanthraquinone
Prabhu, V. S.,Seshadri, S.
, p. 163 - 164 (2007/10/02)
p-Nitrochlorobenzene (I) condenses with o-carboxyphenylacetonitrile (II) in methanolic potassium hydroxide to produce 3-(2'-carboxyphenyl)-5-chloro-2,1-benzisoxazole (III).Reduction of III leads to a novel synthesis of 2-chloro-6,11(5H)-morphanthridinedione (V) in good yields.The acid catalysed rearrangement of V affords 1-amino-4-hydroxyanthraquinone (VI).
