78633-04-2

Upstream product

• 78632-96-9 5-[2-((4aR,6R,7R,8R,8aR)-7-Acetylamino-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-ethylcarbamoyl]-pentanoic acid methyl ester 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 78632-89-0 Acetic acid (2R,3R,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-azido-6-(2-{[1-phenyl-meth-(Z)-ylidene]-amino}-ethoxy)-tetrahydro-pyran-4-yl ester 
• 78632-92-5 5-[2-((4aR,6S,7R,8R,8aR)-7-Acetylamino-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-ethylcarbamoyl]-pentanoic acid methyl ester 
• 78632-92-5 <2-(4-Methoxycarbonylbutancarboxamido)ethyl>-2-acetamido-4,6-O-benzyliden-2-desoxy-β-D-galactopyranosyd 
• 67817-37-2 3,4,6-tri-O-acetyl-2-azido-2-deoxy-β-D-galactopyranosyl chloride 
• 82743-64-4 Acetic acid (2R,3R,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-6-(2-amino-ethoxy)-5-azido-tetrahydro-pyran-4-yl ester 
• 78632-92-5 <2-(4-Methoxycarbonylbutancarboxamido)ethyl>-2-acetamido-4,6-O-benzyliden-2-desoxy-α-D-galactopyranosid 
• 78632-91-4 <2-(4-Methoxycarbonylbutancarboxamido)ethyl>-2-acetamido-2-desoxy-α-D-galactopyranosid 
• 78632-90-3 5-[2-((2S,3R,4R,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-azido-tetrahydro-pyran-2-yloxy)-ethylcarbamoyl]-pentanoic acid methyl ester 
• 78632-95-8 <2-(4-Methoxycarbonylbutancarboxamido)ethyl>-2-acetamido-2-desoxy-β-D-galactopyranosid 

Downstream Products

• 78633-00-8 <2-(4-Methoxycarbonylbutancarboxamido)ethyl>-2-acetamido-6-O-benzoyl-2-desoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyd 
• 78633-06-4 <2-(4-Methoxycarbonylbutancarboxamido)ethyl>-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-4)>-2-acetamido-6-O-benzoyl-2-desoxy-α-D-galactopyranosyd 

Relevant academic research and scientific papers

Synthesis of oligosaccharide determinants with amide spacers of T-type antigens

The hapten of the T-antigen was synthesized with a peptide-like amide-spacer as 2-(4-methoxycarbonylbutanecarboxamido)ethyl 2-acetamido-2-deoxy-3-O-beta-D-galactopyranosyl-alpha-D-galactopyranoside and coupled with serum albumin to give a synthetic antigen. Other O-beta-D-galactopyranosyl haptens, 2-(4-methoxycarbonylbutanecarboxamido)ethyl 2-acetamido-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-galactopyranoside, O-beta-D-galactopyranosyl-(1 leads to 3)-O-[beta-D-galactopyranosyl-(1 leads to 4)]-2-acetamido-2-deoxy-alpha-D-galactopyranoside, and 2-acetamido-2-deoxy-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside, the last compound being the determinant of the Lewis Lec antigen, were also synthesized.

SYNTHESE VON OLIGOSACCHARID-DETERMINANTEN DES T-ANTIGENS MIT AMID-SPACER ZUR DARSTELLUNG SYNTHETISCHER ANTIGENE

The β(1->3)-linked disaccharide 15 was synthesized from D-galactose and D-galactosamine unit with a watersoluble amide spacer.This represents the hapten of T-antigen and, when coupled to a protein, is suitable for use as an artificial antigen.Other O-β-D-