78633-78-0

Basic information

• Product Name: 4-allyloxy-2-hydroxy-3-iodo-6-methoxybenzoylacetone
• Synonyms: 4-allyloxy-2-hydroxy-3-iodo-6-methoxybenzoylacetone
• CAS NO: 78633-78-0
• Molecular Weight: 390.175
• Mol File: 78633-78-0.mol

Chemical Properties

• CAS DataBase Reference: 4-allyloxy-2-hydroxy-3-iodo-6-methoxybenzoylacetone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-allyloxy-2-hydroxy-3-iodo-6-methoxybenzoylacetone(78633-78-0)
• EPA Substance Registry System: 4-allyloxy-2-hydroxy-3-iodo-6-methoxybenzoylacetone(78633-78-0)

Safety Data

• Hazardous Substances Data: 78633-78-0(Hazardous Substances Data)

Upstream product

• 74047-33-9 4-allyloxy-2-hydroxy-3-iodo-6-methoxyacetophenone 
• 141-78-6 ethyl acetate 

Downstream Products

• 82-57-5 visnagin 
• 4481-60-1 5-norvisnagin 

Relevant articles and documents

SELECTIVE CLAISEN MIGRATION IN CHROMONES. A CONVENIENT SYNTHESIS OF THE LINEAR FURANOCHROMONES DESMETHOXYVISNAGIN, NORVISNAGIN, and VISNAGIN

A convenient synthesis of furanochromones, viz. 7-methyl-5H-furobenzopyran-5-one (desmethoxyvisnagin), 4-hydroxy-7-methyl-5H-furobenzopyran-5-one (norvisnagin), and 4-methoxy-7-methyl-5H-furobenzopyran-5-one (visnagin) is described.The synthesis utilises blocking the 8-position of the corresponding 7-allyloxychromone derivative with iodine, Claisen migration, followed by oxidation and subsequent cyclo-dehydration.