78640-18-3Relevant academic research and scientific papers
Enantioselective bromolactonization of aryl functionalized alkenoic acids
Hansen, Trond Vidar,Kristianslund, Renate
supporting information, (2020/03/04)
Aryl substituted 1,1-disubstituted alkenoic carboxylic acids were subjected to an enantioselective organocatalyzed protocol, yielding the corresponding δ-bromolactones in a regioselective manner. The products were isolated in good to high yields with enantiomeric excess in the range of 18–88%.
Cross-Electrophile Coupling of Vinyl Halides with Alkyl Halides
Johnson, Keywan A.,Biswas, Soumik,Weix, Daniel J.
supporting information, p. 7399 - 7402 (2016/05/24)
An improved method for the reductive coupling of aryl and vinyl bromides with alkyl halides that gave high yields for a variety of substrates at room temperature with a low (2.5 to 0.5 mol %) catalyst loading is presented. Under the optimized conditions, difficult substrates, such as unhindered alkenyl bromides, can be coupled to give the desired olefins with minimal diene formation and good stereoretention. These improved conditions also worked well for aryl bromides. For example, a gram-scale reaction was demonstrated with 0.5 mol % catalyst loading, whereas reactions at 10 mol % catalyst loading completed in as little as 20 minutes. Finally, a low-cost single-component pre-catalyst, (bpy)NiI2 (bpy=2,2′-bipyridine) that is both air- and moisture-stable over a period of months was introduced.
ARYLATION AND VINYLATION OF 2-CARBOETHOXYETHYLZINC IODIDE AND 3-CARBOETHOXYPROPYLZINC IODIDE CATALYZED BY PALLADIUM
Tamaru, Y.,Ochiai, H.,Nakamura, T.,Yoshida, Z.
, p. 955 - 958 (2007/10/02)
By the palladium catalysis 2-carboethoxyethylzinc iodide reacts with aryl iodides and vinyl iodides or triflates to provide the coupling products (ethyl 3-arylpropionates and ethyl 4-pentenoates, respectively) in satisfactory yields.The similar coupling reaction is observed for the reaction with 3-carboethoxypropylzinc iodide.
A NEW SYNTHETIC METHOD: DIRECT REPLACEMENT OF THE NITRO GROUP BY HYDROGEN OR DEUTERIUM
Ono, Noburu,Miyake, Hideyoshi,Tamura, Rui,Kaji, Aritsune
, p. 1705 - 1708 (2007/10/02)
The nitro group in tertiary and secondary aliphatic nitro compounds is replaced by hydrogen or deuterium on treatment with tributyltin hydride or tributyltin deuteride, respectively.
