78649-11-3Relevant academic research and scientific papers
Modification of the Pictet-Spengler reaction in the synthesis of fused 2,3-benzodiazocines
Tolkunov,Baumer,Palamarchuk,Shishkin,Mazepa,Tolkunov,Bogza
experimental part, p. 1006 - 1013 (2012/03/26)
A new strategy for the synthesis of the eight-membered heterocyclic skeleton of tetrahydro-quinazolino[3,2-c][2,3]benzodiazocin-15-ones, based on the Pictet-Spengler reaction of 3-amino-2-[2-(3,4-dimethoxyphenyl)ethyl] quinazolin-4(3H)-one with carbonyl c
Intramolecular Reactions of N-Nitrenes: Oxidation of 3-Amino-2-(arylalkyl)quinazolin-4(3H)-ones
Atkinson, Robert S.,Malpass, John R.,Woodthorpe, Katherine L.
, p. 2407 - 2412 (2007/10/02)
Oxidation of the title compounds yields N-nitrenes which react intramolecularly with methoxy-substituted aryl rings.The particular substitution pattern in the aryl rings which is required for effective trapping of the nitrenes is in accord with an electro
Intramolecular Reactions of N-Nitrenes: Oxidation of 3-Amino-2-(arylalkyl)quinazolones
Atkinson, Robert S.,Malpass, John R.,Woodthorpe, Katherine L.
, p. 160 - 162 (2007/10/02)
Oxidation of the title compounds yields N-nitrenes which react intramolecularly with electron-rich aryl groups via 7-membered transition states; substituent effects are in accord with an electrophilic aromatic substitution rather than concerted addition.
