786602-87-7Relevant academic research and scientific papers
AGENTS THAT INHIBIT NGLY1 AND METHODS OF USE THEREOF
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, (2018/08/26)
Methods are provided for treatment of cancer cells, in a regimen comprising contacting the cancer cells with an inhibitor on NGly1, optionally in combination with a direct proteasome inhibitor.
Design, synthesis and evaluation of 3-methylene-substituted indolinones as antimalarials
Praveen Kumar,Gut, Jiri,Guedes, Rita C.,Rosenthal, Philip J.,Santos, Maria M.M.,Moreira, Rui
, p. 927 - 933 (2011/04/16)
The design, synthesis and evaluation of 3-methylene-substituted indolinones as falcipain inhibitors and antiplasmodial agents are described. These compounds react readily with thiols via an addition-elimination mechanism, indicating their potential as cys
