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Z-pGlu-Leu-pyrrolidide is a synthetic tripeptide composed of three amino acids: glutamic acid (Glu), leucine (Leu), and a pyrrolidide group. The "Z" prefix in its name stands for the benzyloxycarbonyl (Cbz) protecting group, which is commonly used in peptide synthesis to prevent unwanted side reactions. This peptide is of interest in the field of medicinal chemistry and drug development, as it may exhibit biological activity or serve as a building block for more complex peptide structures. The presence of the pyrrolidide group, which is a cyclic amide formed by the intramolecular reaction of the carboxyl group with the amino group of the terminal amino acid, contributes to the stability and potential pharmacological properties of the peptide.

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  • 78664-60-5 Structure
  • Basic information

    1. Product Name: Z-pGlu-Leu-pyrrolidide
    2. Synonyms: Z-pGlu-Leu-pyrrolidide
    3. CAS NO:78664-60-5
    4. Molecular Formula:
    5. Molecular Weight: 429.516
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 78664-60-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Z-pGlu-Leu-pyrrolidide(CAS DataBase Reference)
    10. NIST Chemistry Reference: Z-pGlu-Leu-pyrrolidide(78664-60-5)
    11. EPA Substance Registry System: Z-pGlu-Leu-pyrrolidide(78664-60-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 78664-60-5(Hazardous Substances Data)

78664-60-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78664-60-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,6,6 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 78664-60:
(7*7)+(6*8)+(5*6)+(4*6)+(3*4)+(2*6)+(1*0)=175
175 % 10 = 5
So 78664-60-5 is a valid CAS Registry Number.

78664-60-5Downstream Products

78664-60-5Relevant articles and documents

Synthesis of Thyrotropin-Releasing Hormone Analogues. 1. Complete Dissociation of Central Nervous Effects from Thyrotropin-Releasing Activity

Szirtes, Tamas,Kisfaludy, Lajos,Palosi, Eva,Szporny, Laszlo

, p. 741 - 745 (1984)

Twenty-four thyrotropin-releasing hormone (TRH) analogues containing mainly aliphatic amino acids in position 2 were synthesized and tested for central nervous system (CNS) and hormonal (TSH) activity.Application of the pentafluorophenyl ester method in t

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