786654-97-5

Basic information

• Product Name: 2-(3-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: 2-(3-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;ethyl 2-(3-bromophenyl)thiazole-4-carboxylate
• CAS NO: 786654-97-5
• Molecular Formula: C₁₂H₁₀BrNO₂S
• Molecular Weight: 312.18
• EINECS: 604-604-1
• Mol File: 786654-97-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 415.2°C at 760 mmHg
• Flash Point: 204.9°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 4.2E-07mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(3-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER(786654-97-5)
• EPA Substance Registry System: 2-(3-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER(786654-97-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 786654-97-5(Hazardous Substances Data)

Usage

General Description

2-(3-Bromo-phenyl)-thiazole-4-carboxylic acid ethyl ester is a chemical compound with the molecular formula C12H9BrNO2S. It is a derivative of thiazole and contains both a bromine atom and a carboxylic acid ethyl ester functional group. 2-(3-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER is commonly used in the field of medicinal chemistry for the synthesis of pharmaceuticals and agrochemicals. It may also have potential applications in the development of novel materials and as a building block in organic synthesis. The specific properties and uses of this compound are dependent on its structure and reactivity, which can be further explored and investigated in various chemical and biological studies.

InChI:InChI=1/C12H10BrNO2S/c1-2-16-12(15)10-7-17-11(14-10)8-4-3-5-9(13)6-8/h3-7H,2H2,1H3

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 868-59-7 L-cysteine ethyl ester hydrochloride 
• 6952-59-6 3-cyanobromobenzene 
• 100367-77-9 ethyl 2-bromothiazole-4-carboxylate 
• 89598-96-9 (3-bromophenyl)boronic acid 
• 2227-62-5 3-bromothiobenzamide 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 885280-57-9 [3-(bromo-phenyl)-thiazol-4-yl]-methanol 

Relevant articles and documents

I2/TBHP-Mediated tandem cyclization and oxidation reaction: Facile access to 2-substituted thiazoles and benzothiazoles

The efficient synthesis of 2-substituted thiazoles and benzothiazoles has been accomplished employing readily available cysteine esters and 2-aminobenzenethiols as N and S sources. The reaction proceeds under an I2/TBHP system and involves a on

ALKYNYL ALCOHOLS AND METHODS OF USE

The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over- activation of NF-kB signaling is observed.

SUBSTITUTED HETEROARYL CARBOXYLIC ACID DERIVATIVES AS PTB-1B INHIBITORS

Disclosed are compounds and pharmaceutically acceptable salts of formula (I) : which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of the invention include inhibitors of Pr