786665-99-4

Upstream product

• 86945-40-6 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranuronic acid 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 331729-03-4 (2S,3S,4R,5R)-3-azido-5-(6-chloro-purin-9-yl)-4-acetoxy-tetrahydro-furan-2-carboxylic acid methylamide 
• 331729-04-5 3-azido-3-deoxy-1,2-diacetoxy-α-D-ribofuranuronic acid methyl amide 
• 86945-41-7 1,2-O-isopropylidene-3-azido-3-deoxy-α-D-ribofuranuronic acid methyl ester 
• 23345-80-4 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose 
• 331729-05-6 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranuronic acid methyl amide 
• 55951-93-4 1,2:5,6-di-O-isopropylidene-3-O-triflyl-α-D-glucofuranose 
• 21870-78-0 3-azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 35085-25-7 3-azido-3-deoxy-1,2-O-isopropylidene-α-D-allofuranose 
• 3718-88-5 3-iodobenzylamine hydrochloride 

Downstream Products

• 786666-03-3 3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-t-butyldimethylsiloxy-tetrahydro-furan-2-carboxylic acid methyl amide 
• 786666-07-7 3-amino-5-(6-(3-iodobenzylamino)purin-9-yl)-4-t-butyldimethylsiloxy-tetrahydro-furan-2-carboxylic acid methyl amide 
• 786666-15-7 3-ureido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-t-butyldimethylsiloxy-tetrahydro-furan-2-carboxylic acid methyl amide 
• 786666-11-3 3-(3-chloroacetylureido)-5-(6-(3-iodobenzylamino)purin-9-yl)-4-t-butyldimethylsiloxy-tetrahydro-furan-2-carboxylic acid methyl amide 

Relevant academic research and scientific papers

Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists

An alternative approach to overcome the inherent lack of specificity of conventional agonist therapy can be the reengineering of the GPCRs and their agonists. A reengineered receptor (neoceptor) could be selectively activated by a modified agonist, but no

Exploring human adenosine A3 receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety

In this paper we investigated the influence on affinity, selectivity and intrinsic activity upon modification of the adenosine agonist scaffold at the 3′- and 5′-positions of the ribofuranosyl moiety and the 2- and N6-positions of the purine ba

Design and synthesis of 3′-ureidoadenosine-5′-uronamides: Effects of the 3′-ureido group on binding to the A3 adenosine receptor

Novel 3′-ureidoadenosine analogues, 3 and 4 were synthesized from 1,2:5,6-di-O-isopropylidene-d-glucose in order to cause stronger hydrogen bonding than the corresponding 3′-aminoadenosine derivatives at the A 3 adenosine receptor. On the basis