78679-34-2Relevant academic research and scientific papers
One-pot Synthesis of Secondary or Tertiary Amines from Alcohols and Amines via Alkoxyphosphonium Salts
Froyen, Paul,Juvvik, Paul
, p. 9555 - 9558 (1995)
Secondary or tertiary amines may be prepared from primary alcohols and primary or secondary amines by treating triphenylphosphine with N-bromosuccinimide (NBS) in the presence of the alcohol at low temperature, followed by addition of the amine and heating for about 1 h.The yield of amine is good to fair, decreasing sharply with sterically congested alcohols and starting amines.
Hydrophobic amplification of noncovalent organocatalysis
Kleiner, Christian M.,Schreiner, Peter R.
, p. 4315 - 4317 (2007/10/03)
The effects of hydrogen-bonding organocatalysts and water for the acceleration of epoxide openings with a variety of nucleophiles are additive and lead to excellent yields of the catalyzed reactions in water. The Royal Society of Chemistry 2006.
