78712-57-9

Basic information

• Product Name: 1-Octanone, 8-bromo-1-phenyl-
• CAS NO: 78712-57-9
• Molecular Formula: C14H19BrO
• Molecular Weight: 283.208
• Mol File: 78712-57-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Octanone, 8-bromo-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Octanone, 8-bromo-1-phenyl-(78712-57-9)
• EPA Substance Registry System: 1-Octanone, 8-bromo-1-phenyl-(78712-57-9)

Safety Data

• Hazardous Substances Data: 78712-57-9(Hazardous Substances Data)

Upstream product

• 7287-06-1 1-phenyl-1-cyclooctanol 
• 73674-09-6 8-bromo-n-octanoyl chloride 

Downstream Products

• 78712-50-2 8-Imidazol-1-yl-1-phenyl-octan-1-one 

Relevant articles and documents

Visible-light-enhanced ring opening of cycloalkanols enabled by br?nsted base-tethered acyloxy radical induced hydrogen atom transfer-electron transfer

A metal-free ring opening/halogenation of cycloalkanols, which combines both PPO/TBAX oxidant system and blue LEDs irradiation, is presented. This method produces diverse γ, α, and even more remotely halogenated ketones in moderate to excellent yields under mild conditions. Interestingly, experimental and computational studies demonstrate the novel ring size-dependent concerted/stepwise (four-/five- to eight-membered rings) hydrogen atom transfer-electron transfer induced by Br?nsted base-tethered acyloxy radical, which indicates distinct advantages brought by the cyclic structure of diacyl peroxides.

BENZOIC ACID COMPOUNDS AND USE THEREOF AS MEDICAMENTS

Benzoic acid compounds of the formula STR1 wherein each symbol is as defined in the specification, optical isomers thereof and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising this compound and pharmaceutically acceptable additive; and serotonin 4 receptor agonists, gastrointestinal prokinetic agents and therapeutic agents for various gastrointestinal diseases, which comprise this compound as active ingredient. The compounds of the present invention have high and selective affinity for serotonin 4 receptor, and show agonistic effects thereon. Accordingly, they are useful medications for the prophylaxis and treatment of various gastrointestinal diseases, central nervous disorders, cardiac function disorders, urinary diseases, and the like, as well as useful anti-nociceptors for analgesic use which increase threshold of pain.