78723-40-7Relevant academic research and scientific papers
NEW BORANE-AMINE COMPLEXES AND THEIR APPLICATION IN SUZUKI-TYPE CROSS -COUPLING REACTIONS
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Page/Page column 10-11, (2009/12/05)
The invention relates to new amine complexes of B-organyl-9-borabicyclo[3.3.1]nonanes and to solutions of said complexes. Furthermore, the invention relates to a method of using trialkylborane-amine complexes in Suzuki-type cross-coupling reactions and to a process to form new carbon-carbon bonds in a Suzuki-type cross-coupling reaction with a triorganoborane, which is carried out in the presence of an amine.
Palladium-Catalyzed Cross-Coupling Reaction of Organoboron Compounds with Organic Triflates
Oh-e, Takayuki,Miyaura, Norio,Suzuki, Akira
, p. 2201 - 2208 (2007/10/02)
The cross-coupling reaction of 9-alkyl-9-borabicyclononane (9-R-9-BBN), 1-alkenyl-1,3,2-benzodioxaborole, or aryl boronic acid with 1-alkenyl or aryl triflates in the presence of K3PO4 (1.5 equiv) and a catalytic amount of Pd(PPh3)4 or Cl2Pd(dppf) resulted in high yields.The reaction conditions are sufficiently mild so that a variety of functionalized alkenes, alkadienes, and arenes are readily obtained.The utility of the present reaction was demonstrated by the cyclization of ω-alkenyl triflates leading to a benzo-fused cycloalkene and bicyclic alkene via a hydroboration intramolecular coupling sequence.
