78727-45-4

Upstream product

• 108-24-7 acetic anhydride 
• 77362-54-0 2,5-Dihydro-2-methyl-α-phenylhydrazono-2-thiazolessigsaeure-methylester 
• 77362-57-3 (Z)-3-Amino-2-phenylazo-but-2-enoic acid methyl ester 
• 14205-39-1 methyl 3-aminocrotonate 
• 13732-25-7 methyl 2-phenylhydrazono-3-oxobutyrate 
• 77362-57-3 3-Amino-2-phenylazo-2-butensaeure-methylester 
• 100-34-5 benzene diazonium chloride 

Relevant academic research and scientific papers

SYNTHESIS AND ACYLATION OF (2,5-DIHYDRO-1,3-THIAZOL-2-YL)-2-PHENYLHYDRAZONOACETIC ACID ESTERS

The preparation of 2-(2,5-dihydro-1,3-thiazol-2-yl)-2-phenylhydrazonoacetic acid esters is described.Acylation of these compounds occurs at the sulfur atom with concomitant opening of the dihydrothiazole ring to yield 3-(Z-2-acylthiovinylimino)-2-phenylhydrazono-butanoic acid esters.

Synthesis of α-Arylhydrazono-2,5-dihydro-2-methyl-2-thiazoleacetic Esters and its Rearrangement by Electrophilic Attack

Two pathways to 3-amino-2-arylazo-2-butenoic esters 6 starting from acetoacetic esters have been investigated.The esters 6 can be converted with oligomeric α-mercaptoaldehydes to α-arylhydrazono-2,5-dihydro-2-methyl-2-thiazoleacetic esters 2 and 9.Acylati