78733-52-5Relevant academic research and scientific papers
Convenient synthesis of O-functionalized mandelic acids via Lewis acid mediated transformation of 1,3-dioxolan-4-ones
Shcherbinin, Vitaly A.,Konshin, Valery V.
, p. 3570 - 3578 (2019/05/24)
An efficient method for the synthesis of O-substituted mandelic acids containing alkenyl, alkynyl, methoxycarbonyl, or phenacyl fragments via the Lewis acid-catalyzed reaction of 1,3-dioxolan-4-ones with different C-nucleophiles is proposed.
Lewis acid-mediated mono- and bis-addition of C-nucleophiles to 1,3-dioxolan-4-ones
Shcherbinin, Vitaly A.,Konshin, Valery V.
supporting information, p. 3005 - 3009 (2018/07/06)
The reactions of 1,3-dioxolan-4-ones, readily available from α-hydroxy acids and aldehydes, with C-nucleophiles are described. Two possible reaction pathways resulting in O-substituted acids and tri-(hetero)arylmethanes are shown.
Flash Vacuum Thermolysis of 1,3-Dioxolan-4-ones
Cameron, Tim B.,El-Kabbani, Fiesal M.,Pinnick, Harold W.
, p. 5414 - 5417 (2007/10/02)
Flash vacuum thermolysis of 1,3-dioxolane-4-ones yields aldehydes and ketones as the major products as the result of apparent decarboxylation of α lactones formed by collapse of a 1,3 dipole.When phenyl substituents are present, epoxides are also formed via the intermediacy of a carbonyl ylide.
