78748-23-9Relevant academic research and scientific papers
INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF
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, (2022/01/12)
Disclosed herein are synthesis and use of covalent inhibitors selective for Transcriptional Enhancer Factor TEF-1 (TEAD1), which can be used for treatment of cancers such as glioblastoma, gastric cancer, colorectal cancer, pancreatic ductal adenocarcinoma (PDAC), and malignant pleural mesothelioma (MPM). Further disclosed herein are pharmaceutical compositions including the TEAD1 inhibitor and methods of treating cancers using the same.
HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6
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Paragraph 00539-00540, (2021/09/04)
The present disclosure relates to compounds capable of modulating the activity of NR2F6. The compounds of the disclosure may be used in methods for the prevention and/or the treatment of diseases and disorders associated with modulating NR2F6 activity.
Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
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, (2008/06/13)
A compound having the following formula: wherein R3and M are defined herein, and processes therewith.
