787615-01-4 Usage
Uses
Used in Pharmaceutical and Organic Synthesis Industries:
ISOQUINOLINE-8-CARBALDEHYDE is used as a chemical building block for its role in the synthesis of various pharmaceuticals and organic compounds. Its capacity to form stable complexes with transition metals makes it a valuable component in catalytic and synthesis reactions, contributing to the development of new and improved products in these industries.
Used as a Flavoring and Fragrance Agent:
In the flavoring and fragrance industry, ISOQUINOLINE-8-CARBALDEHYDE is utilized for its strong, pungent odor, adding depth and complexity to the scents and tastes of various consumer products.
Used in the Production of Pharmaceuticals and Agrochemicals:
ISOQUINOLINE-8-CARBALDEHYDE is used as a key intermediate in the manufacturing process of pharmaceuticals and agrochemicals, playing a crucial role in the development of new drugs and agricultural products.
Used in Catalytic and Synthesis Reactions:
Due to its ability to form stable complexes with transition metals, ISOQUINOLINE-8-CARBALDEHYDE is employed in various catalytic and synthesis reactions, enhancing the efficiency and effectiveness of these processes.
Used for Antimicrobial and Insecticidal Properties:
ISOQUINOLINE-8-CARBALDEHYDE has been investigated for its potential antimicrobial and insecticidal properties, indicating its use in applications that require the control of microorganisms and insects, such as in the development of new antimicrobial agents and insecticides.
Check Digit Verification of cas no
The CAS Registry Mumber 787615-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,7,6,1 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 787615-01:
(8*7)+(7*8)+(6*7)+(5*6)+(4*1)+(3*5)+(2*0)+(1*1)=204
204 % 10 = 4
So 787615-01-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H7NO/c12-7-9-3-1-2-8-4-5-11-6-10(8)9/h1-7H
787615-01-4Relevant articles and documents
Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH-102
Haym, Isabell,Huynh, Tri H. V.,Hansen, Stinne W.,Pedersen, Martin H. F.,Ruiz, Josep A.,Erichsen, Mette N.,Gynther, Mikko,Bj?rn-Yoshimoto, Walden E.,Abrahamsen, Bjarke,Bastlund, Jesper F.,Bundgaard, Christoffer,Eriksen, Anette L.,Jensen, Anders A.,Bunch, Lennart
, p. 403 - 419 (2016)
Although the selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor UCPH-101 has become a standard pharmacological tool compound for in vitro and ex vivo studies in the EAAT research field, its inability to penetrate the blood-brain barrier makes it unsuitable for in vivo studies. In the present study, per os (p.o.) administration (40 mg kg-1) of the closely related analogue UCPH-102 in rats yielded respective plasma and brain concentrations of 10.5 and 6.67 μm after 1 h. Three analogue series were designed and synthesized to improve the bioavailability profile of UCPH-102, but none displayed substantially improved properties in this respect. In vitro profiling of UCPH-102 (10 μm) at 51 central nervous system targets in radioligand binding assays strongly suggests that the compound is completely selective for EAAT1. Finally, in a rodent locomotor model, p.o. administration of UCPH-102 (20 mg kg-1) did not induce acute effects or any visible changes in behavior. EAAT1 inhibition beyond the BBB: In the present study, oral administration (40 mg kg-1) of the selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor UCPH-102 in rats yielded respective plasma and brain concentrations of 10.5 and 6.67 μm after 1 h. In vitro profiling of UCPH-102 (10 μm) at 51 central nervous system targets in radioligand binding assays strongly suggests that the compound is fully selective for EAAT1.
