787618-01-3Relevant academic research and scientific papers
Diastereoselective [2+2]-cycloaddition reactions of unsymmetrical cyclic ketenes with imines: Synthesis of modified prolines and theoretical study of the reaction mechanism
Macias, Alberto,Alonso, Eduardo,Del Pozo, Carlos,Venturini, Alessandro,Gonzalez, Javier
, p. 7004 - 7012 (2007/10/03)
The synthesis of enantiomerically pure modified proline derivatives was achieved by using spiro β-lactams as starting material that were prepared in turn by the [2+2]-cycloaddition of unsymmetrical cyclic ketenes with optically active imines. A theoretica
