787629-77-0Relevant academic research and scientific papers
Highly diastereoselective reduction of β-ketophosphonates bearing homochiral bis(α-methylbenzyl)amine: Preparation of both enantiomers of phosphogabob (GABOBP)
Ordonez, Mario,Gonzalez-Morales, Angelina,Salazar-Fernandez, Humberto
, p. 2719 - 2725 (2007/10/03)
The reduction of dimethyl 3-N,N-di(α-methylbenzyl)amino-2- ketophosphonates 9 with catecholborane at -78°C in presence of LiClO 4, gave γ-amino-β-hydroxyphosphonates 10 and 11 in good yield and with excellent diastereoselectivity. This procedur
