78771-74-1Relevant articles and documents
Probable role of clavaminic acid as the terminal intermediate in the common pathway to clavulanic acid and the antipodal clavam metabolites
Egan, Laura A.,Busby, Robert W.,Iwata-Reuyl, Dirk,Townsend, Craig A.
, p. 2348 - 2355 (2007/10/03)
Emerging chemical and genetic evidence suggests that separate biochemical solutions have evolved to synthesize the four known classes of β-lactam antibiotics. One of these classes contains clavulanic acid (1) and a family of structurally related but antip