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Salicylidene p-aminophenol, also known as 2-salicylidene-1-(p-aminophenyl)ethanone, is an organic compound with the chemical formula C15H13NO2. It is a derivative of salicylaldehyde and p-aminophenol, characterized by a salicylaldehyde group attached to an acetophenone molecule through an imine linkage. This yellow crystalline solid is used as an intermediate in the synthesis of various pharmaceuticals, dyes, and other organic compounds. Its chemical structure and reactivity make it a versatile building block in organic synthesis, particularly in the preparation of complex molecules with potential applications in the medical and chemical industries.

788-23-8

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788-23-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 788-23-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,8 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 788-23:
(5*7)+(4*8)+(3*8)+(2*2)+(1*3)=98
98 % 10 = 8
So 788-23-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO2/c1-11(17)12-6-8-14(9-7-12)16-10-13-4-2-3-5-15(13)18/h2-10,16H,1H3

788-23-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (6E)-6-[(4-acetylanilino)methylidene]cyclohexa-2,4-dien-1-one

1.2 Other means of identification

Product number -
Other names Salicylidene p-aminoacetophenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:788-23-8 SDS

788-23-8Relevant academic research and scientific papers

Design, spectroscopic properties and effects of novel catechol spiroborates derived from Schiff bases in the antioxidant, antibacterial and DNA binding activity

Kilic, Ahmet,Okumu?, Veysi,S?ylemez, Rahime

, (2021/12/30)

Novel catechol spiroborates (L(1–5)B) were prepared from the reaction of the corresponding Schiff base (L(1–5)H) ligands, boric acid, and 3,5-di?tert?butyl catechol under favorable reaction conditions. The synthesized all compounds w

Schiff base transition metal complexes for Suzuki–Miyaura cross-coupling reaction

Ansari, Rasheeda M,Bhat, Badekai Ramachandra

, p. 1483 - 1490 (2017/09/25)

Abstract: Schiff base ligand and its complex with iron (Fe), cobalt (Co), nickel (Ni) and copper (Cu) ions were synthesized using 4-aminoacetophenone and salicylaldehyde and characterized. FTIR spectrum shows that bidentate coordination of metal ions with ligand where O, N are electron donating sites of azomethine group. The geometry of the complexes was deduced from the calculated magnetic moment values and SCXRD analysis. All complexes were studied for their catalytic activity in Suzuki–Miyaura cross-coupling reaction with Cu–L complex showing excellent coupling yield among others. The catalytic activity data show promising results in coupling efficiency, employing cheap, abundant and green metals. Graphical Abstract: Synopsis The transition metal Schiff base complexes synthesized and characterized by SCXRD, Mass spectrometry, TGA, UV–Vis and FTIR analysis. Magnetic susceptibility measurements were also examined to know the plausible geometry of the complex. The synthesized complexes were systematically investigated for Suzuki–Miyaura cross-coupling reactions and optimized to enhance the yield of the Suzuki reaction. [Figure not available: see fulltext.].

Design, synthesis and in vitro antimalarial evaluation of new quinolinylhydrazone derivatives

Thuy, Le Thi,Tien, Hoang Xuan,Hoang, Vu Dinh,Vu, Tran Khac

scheme or table, p. 163 - 168 (2012/07/17)

A series of novel quinolinylhydrazones (5a-f) was synthesized by the condensation reaction of 2,6-diaryl-substituted piperidin-4-ones (4a-f) with 7-chloro-4-hydrazinoquinoline (2). Novel quinolinylhydrazones containing Shiff bases 8a-f and 11a-f were obta

The substituent effects on the 13C chemical shifts of the azomethine carbon atom of N-(substituted phenyl)salicylaldimines

Drmanic, Sasa Z.,Marinkovic, Aleksandar D.,Nikolic, Jasmina B.,Jovanovic, Bratislav Z.

, p. 993 - 1001 (2012/10/29)

Hammett correlations between the 13C-NMR chemical shifts of the azomethine carbon atom and the corresponding substituent constants were established for thirteen Schiff bases. The successful correlation of the chemical shifts with the electrophilic substituent constants σ+ indicate a significant resonance interaction of the substituents on the aniline ring with the azomethine carbon atom in the examined series of imines. The demand for electrons in the investigated compounds was compared to that of the N-benzylideneanilines and N-(substituted phenyl)pyridinealdimines. The manner of transmission of the substituent effects is discussed and they were separated into resonance and inductive effects. The inductive effects prevail over the resonance effects.

Mixed ligand complexes of cobalt(II and III) - Molecular structure of bis-(4-acetophenylsalicylaldiminato)acetylacetonato cobalt(III)

De Lal,Banerjee,Mukherjee,Guha

, p. 1050 - 1054 (2007/10/03)

The bidentate Schiff bases, HL′(= N-4-acetophenylsalicylal-dimine), H″(=N-3-acetophenylsalicylaldimine) and HL? (=N-4-acetophenyl-5-bromosalicylaldimine) do not form complexes with simple cobalt(II)salts, e.g.,Co(CH3COO)2.4H2/s

Exchange of amine part of schiff bases with ammonia in presence of a metal ion: Molecular structure of bis-(salicylaldiminato) nickel(II)

De, Rajib Lal,Banerjee, Indrajit,Samanta, Chitra,Mukherjee, Alok K.

, p. 373 - 376 (2007/10/03)

The schiff bases N-X1-acetophenyl-X2-salicylaldimines (X1=4 or 3; *X2=H or 5Br) inert to complexation with nickel(II) and cobalt(II) salts undergo very prompt reactions when ammonia is added to the reaction mixt

6-[N-(2-Hydroxyphenyl)aminomethylene]-cyclohexa-2,4-dien-1-one

Mukherjee, Alok K.,De Lal, Rajib,Banerjee, Indrajit,Samanta, Chitra,Nayak, Nirmalya P.

, p. 407 - 410 (2007/10/03)

The structure determination of the title compound, C13H11NO2, establishes the tautomeric keto form of the salicylaldimine. The asymmetric unit consists of two crystallographically independent molecules which are essentiall

Synthesis of Some New &β-Lactams, 4-Thiazolidinones and Pyrazolines

Fahmy, A. M.,Hassan, Kh. M.,Khalaf, A. A.,Ahmed, R. A.

, p. 884 - 887 (2007/10/02)

N-Arylidene-p-aminoacetophenone (I) and N-arylidene-4'-aminochalcones (V) have been converted into a series of substituted β-lactams (III) and 4-thiazolidinones (IV), and pyrazolines (VI, VII) respectively. p-Chloroacetamidoacetophenone (II) has also been converted into series of substituted 4'-piperidino/morpholinoacetoamidochalcones (X) which undergo cyclization on treatment with hydrazine, phenylhydrazine or thiourea to pyrazolines (XI, XII) and pyrimidine-2-thiones (XIII) respectively.The antibacterial and antifungal activities of the compounds have been determined.

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