78808-55-6Relevant academic research and scientific papers
Amine-catalyzed asymmetric (3 + 3) annulations of β′-acetoxy allenoates: Enantioselective synthesis of 4H-pyrans
Ni, Chunjie,Tong, Xiaofeng
supporting information, p. 7872 - 7875 (2016/07/07)
The asymmetric (3 + 3) annulations of β′-acetoxy allenoates with either 3-oxo-nitriles or pyrazolones have been realized by using 6′-deoxy-6′-[(l)-N,N-(2,2′-oxidiethyl)-valine amido]quinine (6h) as the catalyst. The three functions of catalyst 6h, including Lewis base (quinuclidine N), H-bond donor (amide NH), and Br?nsted base (morpholine N), cooperatively take crucial roles on the chemo- and enantioselectivity, allowing for the construction of 4H-pyran and 4H-pyrano[2,3-c]pyrazole in high yields and enantioselectivity.
Efficient highly selective synthesis of methyl 2-(ethynyl)alk-2(E)-enoates and 2-(1′-chlorovinyl)alk-2(Z)-enoates from 2-(methoxycarbonyl)-2,3- allenols
Deng, Youqian,Jin, Xin,Fu, Chunling,Ma, Shengming
supporting information; experimental part, p. 2169 - 2172 (2009/09/28)
Highly regio- and stereoselective reactions of readily available 2-(methoxycarbonyl)-2,3-allenols 1 with oxalyl chloride in the presence of Et3N or DMSO afforded methyl 2-(ethynyl)alk-2(E)-enoates(E)-2 and 2-(1′-chlorovinyl)alk-2(Z)-enoates(Z)-
Studies on highly stereoselective addition-elimination reactions of 3-(methoxycarbonyl)-1,2-allen-4-ols with MX. An efficient synthesis of 3-(methoxycarbonyl)-2-halo-1,3(Z)-dienes
Deng, Youqian,Jin, Xin,Ma, Shengming
, p. 5901 - 5904 (2008/02/10)
(Chemical Equation Presented) 3-(Methoxycarbonyl)-2-halo-1,3(Z)-dienes were prepared highly stereoselectively via SN2′-type addition-elimination reactions of 3-(methoxycarbonyl)-1,2-allen-4-ols with MX. These products may easily undergo Negishi
A CONVENIENT SYNTHESIS OF α-HYDROXYALLENES BY THE REACTION OF PROPARGYL IODIDES WITH ALDEHYDES IN THE PRESENCE OF STANNOUS HALIDE
Mukaiyama, Teruaki,Harada, Taira
, p. 621 - 624 (2007/10/02)
In the presence of stannous halide, propargyl iodides react with aldehydes in an aprotic solvent to yield α-hydroxyallenes as major products, particularly in the cases of γ-substituted propargyl iodides, along with β-hydroxyacetylenes.
