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(5E)-5-phenylthio-PGI2 11,15-O-bis(t-butyldimethylsilyl) methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 78824-84-7 Structure
  • Basic information

    1. Product Name: (5E)-5-phenylthio-PGI2 11,15-O-bis(t-butyldimethylsilyl) methyl ester
    2. Synonyms: (5E)-5-phenylthio-PGI2 11,15-O-bis(t-butyldimethylsilyl) methyl ester
    3. CAS NO:78824-84-7
    4. Molecular Formula:
    5. Molecular Weight: 703.187
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 78824-84-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (5E)-5-phenylthio-PGI2 11,15-O-bis(t-butyldimethylsilyl) methyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: (5E)-5-phenylthio-PGI2 11,15-O-bis(t-butyldimethylsilyl) methyl ester(78824-84-7)
    11. EPA Substance Registry System: (5E)-5-phenylthio-PGI2 11,15-O-bis(t-butyldimethylsilyl) methyl ester(78824-84-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 78824-84-7(Hazardous Substances Data)

78824-84-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78824-84-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,8,2 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 78824-84:
(7*7)+(6*8)+(5*8)+(4*2)+(3*4)+(2*8)+(1*4)=177
177 % 10 = 7
So 78824-84-7 is a valid CAS Registry Number.

78824-84-7Relevant articles and documents

SYNTHESIS OF CHEMICALLY STABLE PROSTACYCLIN ANALOGS

Bannai, Kiyoshi,Toru, Takeshi,Oba, Takeo,Tanaka, Toshio,Noriaki, Okamura,et al.

, p. 3807 - 3820 (2007/10/02)

Syntheses of several stable PGI2 analogs substituted by an electron-withdrawing substituent at C-5 or C-7 are described.Reaction of PGI2 methyl ester (1) with benzenesulfenyl chloride gave (5E)-5-phenylthio-PGI2 (2) or (5R)-5-phenylthio-Δ6-PGI1 (5) according to the reaction condition employed.Allyl sulfide 5 was transformed into (7S)-7-hydroxy-PGI2 (11) and (7S)-7-acetoxy PGI2 (12) via stereocontrolled sulfoxide-sulfenate rearrangement, and alcohol 11 was further transformed into (7S)-7-fluoro-PGI2 (14).These PGI2 analogs were found much more stable than PGI2.

STEREOCONTROLLED SYNTHESIS OF 7-HYDROXY- AND 7-ACETOXY-PGI2: NEW STABLE PGI2 ANALOGUES

Bannai, Kiyoshi,Toru, Takeshi,Oba, Takeo,Tanaka, Toshio,Okamura, Noriaki,et al.

, p. 1417 - 1420 (2007/10/02)

Stable analogues of PGI2, 7-hydroxy- and 7-acetoxy-PGI2, were synthesized from protected PGI2 methyl ester 1b via sulfoxides 6a, 6b through stereocontrlled sulfoxide-sulfenate rearrangement.

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