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CAS

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78833-03-1

2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)is a complex organic compound with a unique molecular structure. It is characterized by the presence of a pyridine ring, an amide group, and various alkyl chains. 2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)is a derivative of disopyramide, which is a known antiarrhythmic agent.

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  • alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide

    Cas No: 78833-03-1

  • USD $ 1.9-2.9 / Gram

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  • 78833-03-1 Structure

  • Basic information

    1. Product Name: 2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)-
    2. Synonyms: CM7857; ME 3202; Penticainide; Pentisomide; Propisomide
    3. CAS NO:78833-03-1
    4. Molecular Formula: C19H33N3O
    5. Molecular Weight: 319.48
    6. EINECS: 278-989-5
    7. Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 78833-03-1.mol

  • Chemical Properties

    1. Melting Point: 108-1090C
    2. Boiling Point: 460.5±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 0.987±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
    9. PKA: 15.87±0.50(Predicted)
    10. CAS DataBase Reference: 2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)-(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)-(78833-03-1)
    12. EPA Substance Registry System: 2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)-(78833-03-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 78833-03-1(Hazardous Substances Data)

78833-03-1 Usage

Uses

Used in Pharmaceutical Industry:
2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)is used as a sodium channel blocker for its antiarrhythmic properties. It functions as a class I antiarrhythmic agent, which helps regulate abnormal heart rhythms by blocking sodium channels in cardiac cells, thus stabilizing the heart's electrical activity.
Used in Research and Development:
2-Pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)is also utilized in research and development for the discovery of new drugs and therapeutic agents. Its unique structure and properties make it a valuable tool for studying the mechanisms of action and potential applications in various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 78833-03-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,8,3 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78833-03:
(7*7)+(6*8)+(5*8)+(4*3)+(3*3)+(2*0)+(1*3)=161
161 % 10 = 1
So 78833-03-1 is a valid CAS Registry Number.

78833-03-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Pentisomide

1.2 Other means of identification

Product number -
Other names Propisomide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:78833-03-1 SDS

78833-03-1Downstream Products

78833-03-1Relevant articles and documents

Synthesis and antiarrhythmic activity of new [(dialkylamino)alkyl]pyridylacetamides

Bernhart,Condamine,Demarne,Roncucci,Gagnol,Gautier,Serre

, p. 451 - 455 (2007/10/02)

The synthesis of new [(dialkylamino)alkyl]pyridylacetamides is reported. These compounds displayed a potent antiarrhythmic activity, as demonstrated on a model of myocardial infarction in the conscious dog. Structure-activity relationships are discussed within a series of 22 homologues, comparing relative antiarrhythmic properties and cardiac side effects. One of these compounds, 15, has been selected as a candidate for clinical evaluation in man.

Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants

-

, (2008/06/13)

The present invention relates to new pyridine derivatives of formula: STR1 wherein R1 is an alkyl or an alicyclic group, R2 and R3 are alkyls or alicyclic groups or form an heterocycle with the atom of nitrogen to which they are bonded; the invention also relates to a process for the preparation of said derivatives and the medicines containing at least one of the said derivatives.

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