78859-71-9

Basic information

• Product Name: 3-benzyl-2-hydroxy-1-phenylquinolin-4(1H)-one
• CAS NO: 78859-71-9
• Molecular Formula: C₂₂H₁₇NO₂
• Molecular Weight: 327.3759
• Mol File: 78859-71-9.mol

Chemical Properties

• Boiling Point: 492.1°C at 760 mmHg
• Flash Point: 251.4°C
• Density: 1.296g/cm³
• Vapor Pressure: 1.69E-10mmHg at 25°C
• Refractive Index: 1.693
• CAS DataBase Reference: 3-benzyl-2-hydroxy-1-phenylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-hydroxy-1-phenylquinolin-4(1H)-one(78859-71-9)
• EPA Substance Registry System: 3-benzyl-2-hydroxy-1-phenylquinolin-4(1H)-one(78859-71-9)

Safety Data

• Hazardous Substances Data: 78859-71-9(Hazardous Substances Data)

Upstream product

• 110254-70-1 3-Benzyl-4-chlor-1-phenyl-2(1H)-chinolon 
• 144603-31-6 3-benzyl-3-chloro-1-phenylquinoline-2,4(1H,3H)-dione 
• 1636897-22-7 3-amino-3-benzyl-1-phenylquinoline-2,4(1H,3H)-dione 
• 773837-37-9 sodium cyanide 
• 110216-84-7 4-Amino-3-benzyl-1-phenyl-2(1H)-chinolon 

Downstream Products

• 212517-39-0 2,4-Dioxo-1-phenyl-1,2,3,4-tetrahydroquinoline 
• 144603-31-6 3-benzyl-3-chloro-1-phenylquinoline-2,4(1H,3H)-dione 
• 110254-70-1 3-Benzyl-4-chlor-1-phenyl-2(1H)-chinolon 
• 84261-50-7 3-benzyl-3-hydroxy-1-phenylquinoline-2,4(1H,3H)-dione 
• 110216-95-0 3-Benzyl-1-phenyl-4-tosyloxy-2(1H)-chinolon 
• 110229-50-0 4-Benzylamino-3-benzyl-1-phenyl-2(1H)-chinolon 
• 144603-58-7 3-Benzyl-3-fluoro-1-phenyl-1H-quinoline-2,4-dione 
• 186766-21-2 [3-Benzyl-3-hydroxy-2-oxo-1-phenyl-2,3-dihydro-1H-quinolin-(4E)-ylidene]-acetic acid ethyl ester 

Relevant articles and documents

Reaction of Tertiary 2-Chloroketones with Cyanide Ions: Application to 3-Chloroquinolinediones

3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position

Reduction of 3-aminoquinoline-2,4(1H,3H)-diones and deamination of the reaction products

3-Aminoquinoline-2,4-diones were stereoselectively reduced with NaBH 4 to give cis-3-amino-3,4-dihydro-4-hydroxyquinolin-2(1H)-ones. Using triphosgene (=bis(trichloromethyl) carbonate), these compounds were converted to 3,3a-dihydrooxazolo[4,5-

Methods for the Synthesis of 4-Azido-2(1H)-quinolones

4-Hydroxy-2-quinolones 1 are generally found to be converted to the 4-azidocompounds 3 via the 4-chloroquinolones 2, the 4-tosyloxyquinolones 6, or the 4-aminoquinolones 4, respectively.Choice of the reaction conditions and yields depend on the substituen