78867-72-8

Basic information

• Product Name: 2-Piperidinone, 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-ethyl-3-(phenylsulfinyl)-
• CAS NO: 78867-72-8
• Molecular Formula: C23H29NO4S
• Molecular Weight: 415.554
• Mol File: 78867-72-8.mol

Chemical Properties

• CAS DataBase Reference: 2-Piperidinone, 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-ethyl-3-(phenylsulfinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinone, 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-ethyl-3-(phenylsulfinyl)-(78867-72-8)
• EPA Substance Registry System: 2-Piperidinone, 1-[2-(3,4-dimethoxyphenyl)ethyl]-5-ethyl-3-(phenylsulfinyl)-(78867-72-8)

Safety Data

• Hazardous Substances Data: 78867-72-8(Hazardous Substances Data)

Upstream product

• 78867-71-7 1-(3,4-dimethoxyphenethyl)-5-ethyl-3-phenylthio-2-piperidinone 
• 1027967-90-3 3-benzenesulfinyl-1-[2-(3,4-dimethoxy-phenyl)-ethyl]-5-ethyl-piperidine-2,6-dione 
• 5597-12-6 Phenylmercapto-essigsaeure-homoveratrylamid 
• 14301-31-6 2-chloro-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 444991-98-4 2-benzenesulfinyl-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-acetamide 
• 78867-70-6 1-(3,4-dimethoxyphenethyl)-5-ethyl-2-piperidinone 
• 59033-42-0 1-(3,4-dimethoxy-phenethyl)-5-(2-methyl-[1,3]dithiolan-2-yl)-1H-pyridin-2-one 
• 78867-67-1 4-{[(E)-2-(3,4-Dimethoxy-phenyl)-ethylimino]-methyl}-hexanoic acid methyl ester 
• 78867-69-3 5-ethyl-1-(3,4-dimethoxy-phenethyl)-3,4-dihydro-1H-pyridin-2-one 
• 66757-48-0 methyl 4-formylhexanoate 

Downstream Products

• 56151-99-6 (+/-)-trans-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 78867-74-0 1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidinemalonic acid diethyl ester 
• 56151-96-3 (+/-)-cis-1-(3,4-dimethoxyphenethyl)-2-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 78867-74-0 1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidinemalonic acid diethyl ester 
• 56151-96-3 (+/-)-trans-1-(3,4-dimethoxyphenethyl)-2-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 78867-73-9 1-(3,4-dimethoxyphenethyl)-5-ethyl-5,6-dihydro-2(1H)-pyridinone 

Relevant articles and documents

An efficient synthesis of γ-substituted α,β-unsaturated-δ-lactams. Formal synthesis of (±)-protoemetinol

γ-Substituted α,β-unsaturated δ-lactams 1 was synthesized from α-sulfinyl acetamides 3 in three steps. Formal synthesis of (±)-protoemetinol was also reported.

AN ALTERNATIVE ROUTE TO (+/-)-EMETINE AND (+/-)-DIHYDROCORYNANTHEINE

An alternatie synthesis of (+/-)-emetine(11) and (+/-)-dihydrocorynantheine(13) has been developed in formal sense starting from methyl 3-formylhexanoate(3).