78871-94-0Relevant academic research and scientific papers
Allyl-Nickel Catalysis Enables Carbonyl Dehydrogenation and Oxidative Cycloalkenylation of Ketones
Huang, David,Szewczyk, Suzanne M.,Zhang, Pengpeng,Newhouse, Timothy R.
supporting information, p. 5669 - 5674 (2019/04/26)
We herein disclose the first report of a first-row transition metal-catalyzed α,β-dehydrogenation of carbonyl compounds using allyl-nickel catalysis. This development overcomes several limitations of previously reported allyl-palladium-catalyzed oxidation, and is further leveraged for the development of an oxidative cycloalkenylation reaction that provides access to bicycloalkenones with fused, bridged, and spirocyclic ring systems using unactivated ketone and alkene precursors.
ZUR REGIOSELEKTIVITAET BEIM ALDOL-RINGSCHLUSS
Kreiser, Wolfgang,Below, Peter
, p. 429 - 432 (2007/10/02)
According to the proper choice of reaction conditions, a regioselective ring closure of the 1,5-diketones I is achieved, either to II or III.This directed aldolisation was successfully applied to a short synthesis of the monoterpenoid piperitone.
