104196-99-8

Upstream product

• 5162-44-7 1-bromo-4-butene 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 21889-88-3 hept-6-en-2-one 
• 39257-02-8 3-methyl-hept-6-en-2-one 
• 134834-42-7 ethyl 2-acetyl-2-phenacylhex-5-enoate 
• 946088-32-0 5-(but-3-enyl)-6-methyl-2-phenyl-pyrimidin-4-ol 
• 139061-19-1 3-benzyloxycarbonyl-2,7-dimethyl-8-ethoxycarbonyl-1,6-dioxaspiro<4,5>deca-2,7-diene 
• 421765-87-9 N-Methyl-1-methyl-cis-2-hydroxymethyl-cyclopentylamin; 1t-Methylamino-1r-methyl-2t-hydroxymethyl-cyclopentan 
• 1370590-74-1 ethyl (R)-2-[(S)-1-(tert-butyldiphenylsilanyloxy)ethyl]hex-5-enoate 
• 1370590-76-3 (R)-2-[(S)-1-(tert-butyldiphenylsilanyloxy)ethyl]hex-5-enal 
• 1370590-78-5 tert-butyl[(1S,2S)-1-methyl-2-vinylhex-5-enyloxy]diphenylsilane 
• 1370590-80-9 tert-butyl{(S)-[(S)-1-cyclopent-2-enyl]ethoxy}diphenylsilane 
• 1370590-82-1 (1S,2R,3S)-3-[(S)-1-(tert-butyldiphenylsilanyloxy)ethyl]cyclopentane-1,2-diol` 
• 1370590-84-3 (1R,2S,3S)-3-[(S)-1-(tert-butyldiphenylsilanyloxy)ethyl]cyclopentane-1,2-diol` 
• 1414652-36-0 C₃₀H₄₂O₈ 
• 1414652-42-8 C₂₆H₃₈O₆ 

Relevant academic research and scientific papers

A general synthetic approach to para-cyclophanes via ring-closing metathesis

A new methodology for the synthesis para-cyclophanes and longithorone C frameworks has been demonstrated via alkylation, ceric ammonium nitrate (CAN) oxidation and ring-closing metathesis as key steps.

A general synthetic approach to para-cyclophanes via ring-closing metathesis

A new methodology for the synthesis para-cyclophanes, and longithorone C frameworks has been demonstrated via alkylation, eerie ammonium nitrate (CAN) oxidation and ring-closing metathesis as key steps.

A mild Lewis acid mediated epoxy-ester to bicyclic ortho ester rearrangement

A high yielding rearrangement of epoxy-esters, under Lewis acid conditions, to give bicyclic ortho esters is reported.

Diversity-oriented approach to macrocyclic cyclophane derivatives via ring-closing metathesis

A short synthetic approach to the macrocyclic framework of longithorone C is described via ring-closing metathesis using the Grubbs 2nd generation catalyst. Georg Thieme Verlag Stuttgart ? New York.

New Ugi-Smiles-metathesis strategy toward the synthesis of pyrimido azepines

(Chemical Equation Presented) A new strategy involving Ugi-Smiles coupling followed by ring-closure metathesis is described herein for the preparation of pyrimidine-fused heterocyclic scaffolds. The scope of this sequence is presented in relation with the

Stereospecific syntheses of sex pheromones of the californian red scale and white peach scale (Homoptera: Diaspididae) based on 1,4-cis-hydrogenation of dienes

Stereospecific syntheses of (+/-)-3-methyl-6-isopropenyl-3(Z),9-decadien-1-yl acetate and (+/-)-3,9-dimethyl-6-isopropenyl-3(Z),9-decadien-1-yl propionate (the Racemoc forms of the pheromones of the scales Aonidiella aurantii and Pseudaulascaspis pentagona) with a geometrical purity of the (Z)-trisubstituted double bond not lower than 99percent were performed.The key step in both syntheses was the 1,4-cis-hydrogenation of the corresponding ethyl 3-methyl-6-(1,1-ethylenedioxyethyl)-2,4,9-decatrienoates catalyzed with chromium carbonyl complexes.These 2,4-dienes were obtained in five conventional steps including the alkylation of ethyl acetoacetate by the appropriate 1-bromo-3-butenes and the Horner-Emmons olefination of the corresponding α-branched aldehydes. - Keywords: (+/-)-3-methyl-6-isopropenyl-3(Z),9-decadien-1-yl acetate, (+/-)-3,9-dimethyl-6-isopropenyl-3(Z),9-decadien-1-yl propionate, synthesis, aldehydoketals, ethyl 2,4-alkadienoates, 1,4-cis-hydrogenation, the Horner-Emmons olefination, ethyl acetoacetate, alkylation, arene chromium tricarbonyl complexes

Synthesis of spirocyclic acetals by manganic acetate promoted additions to exocyclic enol ethers

Reaction of β-ketoesters and β-dicarbonyl compounds with manganic acetate in acetic acid gives intermediates, which add to exocyclic enol ethers to afford a variety of interesting spirocyclic acetals. As the exocyclic enol ethers are shown to be readily a

Photochemistry of Cyclic Enones. Part 8. 5-(But-3-enyl)-3-phenylcyclopent-2-enone and 5-(Pent-4-enyl)-3-phenylcyclopent-2-enone

Photolysis of 5-(but-3-enyl)-3-phenylcyclopent-2-enone in benzene solution using Pyrex filter affords two products in the ratio 2:1.These are 1-phenyltricyclo3,8>nonan-7-one and 8-phenyltricyclo3,8>nonan-9-one.They are inseparable by column chromatogryphy, but their structure follows from examination of the four separable lactones derived from the mixture by Baeyer-Villiger oxidation.Photolysis of 5-(pent-4-enyl)-3-phenylcyclopent-2-enone under the same conditions affords only one product, 9-phenyltricyclo3.9>decan-10-one, whose structure follows from examination of the two lactones derived by similar oxidation.These results demonstrate that in these compounds the regioselectivity of ring depends on the length of the 5-side-chain.

Synthesis and X-ray crystal structure determination of 1,3-bridged β-lactams: Novel, anti-Bredt β-lactams

The first successful syntheses of several anti-Bredt β-lactams from alkyl acetoacetate in 11-14 steps are described. The key cyclization reaction involves the Rh(II)-catalyzed carbene insertion of the diazo derivatives 12, 23, and 31 into the N-H bond of the β-lactams. These (±)-1,3-bridged β-lactams have IR absorptions of 1780-1795 cm-1 for the β-lactam carbonyls. The structure of 32d has been determined by X-ray crystallography; this derivative exhibits a C-N (amide) bond length of 1.414 (4) A and a β-lactam pyramid with the nitrogen atom 0.51 A above the basal plane of three carbon atoms.