78874-19-8Relevant academic research and scientific papers
Chemoselective synthesis of quinoxalines and benzimidazoles by silica gel catalysis
Li, Chunmei,Zhang, Furen,Yang, Zhen,Qi, Chenze
supporting information, p. 5430 - 5433 (2014/12/11)
Treatment of nitroolefins and o-phenylenediamine with silica gel catalyst produced quinoxalines mainly in THF, but gave benzimidazoles efficiently in water. Such a solvent-dependent chemoselective reaction has prominent features of affording two cyclized products selectively with the same substrate, short reaction time, operational simplicity, as well as available starting materials and nontoxic catalysts. In addition, the scope and limitations were explored and a plausible reaction mechanism is proposed.
Cu(II)-catalyzed synthesis of quinoxalines from o-phenylenediamines and nitroolefins
Chen, Yongxin,Li, Kangning,Zhao, Mingming,Li, Yuanjiao,Chen, Baohua
supporting information, p. 1627 - 1630 (2013/03/28)
An easy and efficient copper-catalyzed reaction for the synthesis of quinoxalines from o-phenylenediamines and nitroolefins is developed. This reaction could proceed well without additional base and be applied to various available substrates with a one-step synthetic procedure in moderate to good yields.
Some Reactions of β-Aroylacrylic Acid Epoxides
Elkasaby, M. A.,Noureldin, N. A.
, p. 366 - 368 (2007/10/02)
β-Aroylacrylic acids (I) on reaction with hydrogen peroxide give α,β-epoxy-β-aroylacrylic acids (II) which on treatment with sodium hydroxide afford a mixture of arylmethyl 1,2-diketone (III) and arylmethyl glycollic acid (IV).The mixture is separated bei
