78877-70-0

Basic information

• Product Name: 3-benzyl-2-benzylamino-2,5,5-trimethyloxazolidin-4-one
• Synonyms: 3-benzyl-2-benzylamino-2,5,5-trimethyloxazolidin-4-one
• CAS NO: 78877-70-0
• Molecular Weight: 324.423
• Mol File: 78877-70-0.mol

Chemical Properties

• CAS DataBase Reference: 3-benzyl-2-benzylamino-2,5,5-trimethyloxazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-benzylamino-2,5,5-trimethyloxazolidin-4-one(78877-70-0)
• EPA Substance Registry System: 3-benzyl-2-benzylamino-2,5,5-trimethyloxazolidin-4-one(78877-70-0)

Safety Data

• Hazardous Substances Data: 78877-70-0(Hazardous Substances Data)

Upstream product

• 588-46-5 N-(phenylmethyl)acetamide 
• 60110-37-4 N-benzyl-α-bromoisobutyranilide 

Downstream Products

• 115539-58-7 1-(N-benzylcarbamoyl)-1-methylethyl acetate 
• 115539-55-4 3-benzyl-2-ethoxy-2,5,5-trimethyloxazolidin-4-one 
• 115539-61-2 3-benzyl-2-hydroxy-2,5,5-trimethyloxazolidin-4-one 

Relevant articles and documents

Reactions of Amide Anions with α-Bromo-amides

The reactions of α-bromoisobutyramides with the anions from amides and a thioamide afford oxazolidin-4-ones and a thiazolidin-4-one, respectively; these are useful intermediates for preparation of ester derivatives.

CHEMISTRY OF 2-BROMO-2-METHYLPROPANAMIDES. SYNTHESIS AND SOLVOLYTIC BEHAVIOUR OF OXAZOLIDINONES AND SPIRO-OXAZOLIDINONES

The base-promoted reaction of 2-bromo-2-methylpropanamides (1) with 5-, 6-, and 7-membered lactams (2) affords spiro-oxazolidinones (3).The latter compounds are hydrolysed under acidic conditions to yield the ω-aminoester amides (7).The solvolytic behaviour of some monocyclic oxazolidinones obtained upon reaction of common amides with 2-bromoamides (1) is also reported.