78908-29-9Relevant academic research and scientific papers
Aromatic nucleophilic substitution reactions of 2-chloro-1-methylpyridinium iodide with phenols
Kabir, Mahbub,Awwal, Abdul,Hossain, Delwar,Bizly, Nasima K.
, p. 1779 - 1781 (2007/10/03)
The kinetics and mechanism of nucleophilic substitution reactions of 2-chloro-1-methylpyridinium iodide (PI) with different phenols have been studied spectrophotometrically. The reactions are first-order with respect to PI and phenols and the overall reaction order is second. The Bronsted coefficient β for the series is 0.09 ± 0.02, which is in agreement for the nucleophilic substitution reactions. From the Hammett correlation, ρ is found to be -0.29 ± 0.07. Activation parameters for the substitution reactions have been reported. The isokinetic temperature is calculated (321 K) and it is observed that the substitution reactions are enthalpy controlled. A two-step reaction mechanism is consistent with the observed results in which the formation of an intermediate is rate determining.
