78924-18-2Relevant articles and documents
Synthesis of a series of new N1-[4-(4-nitrophenylthio)phenyl]-N3-(H/alkyl/acyl/aryl) thioureas and their antifungal, insecticidal and larvicidal activities
Shankar,Pandeya
, p. 753 - 756 (2007/10/02)
A series of new mono and disubstituted thioureas, derived from 4-(4-nitrophenylthio) aniline, have been prepared and screened for antifungal activity against Alternaria alternata and Curvularia lunata. Their insecticidal and larvicidal activities have also been evaluated against adult male and female cockroaches (Periplanata americana) and mosquito larvae (Culex pipiens fatigans Wied) of IIIrd and early IVth instar stage, respectively. The tabulated results reveal that most of the thiourea derivatives, in general, possess marked antifungal, insecticidal and larvicidal properties, but the chlorosubstituted derivatives, in particular, are the most active compounds in the entire series. Compound 20, n1-[4-(4-nitrophenylthio)phenyl]-N3-(4-chlorophenyl) thiourea, was the most active antifungal compound, whereas, compound 12, N1[4-(4-nitrophenylthio)phenyl]-N3-(4-chlorobenzoyl) thiourea, was the most potent insecticidal and larvicidal compound.