78946-27-7

Upstream product

• 78946-28-8 8-benzyloxy-1-(2'-bromo-4',5'-dimethoxybenzyl)-1,2,3,4-tetrahydro-7-methoxy-N-methylisoquinoline 
• 112378-03-7 8-benzyloxy-1-(2'-bromo-4',5'-dimethoxybenzyl)-7-methoxyisoquinoline 
• 36547-83-8 2-benzoyl-8-benzyloxy-1,2-dihydro-7-methoxy-isoquinoline-1-carbonitrile 
• 36454-39-4 8-Benzyloxy-7-methoxy-2-methyl-isoquinolinium; iodide 
• 78946-29-9 8-Benzyloxy-1-(2-bromo-4,5-dimethoxy-benzyl)-7-methoxy-2-methyl-1,2-dihydro-isoquinoline 
• 53207-00-4 1-bromo-2-(bromomethyl)-4,5-dimethoxybenzene 
• 112378-04-8 8-benzyloxy-1-(2'-bromo-4',5'-dimethoxybenzyl)-7-methoxy-N-methylisoquinolinium iodide 
• 112378-02-6 8-benzyloxy-N-benzoyl-1-(2'-bromo-4',5'-dimethoxybenzyl)-1,2-dihydro-7-methoxyisoquinoline-1-carbonitrile 
• 54370-01-3 1-bromo-2-(chloromethyl)-4,5-dimethoxy-benzene 

Downstream Products

• 113756-78-8 stirene 
• 111000-92-1 1,2,3,4-Tetrahydro-1-(3',4'-dimethoxybenzyl)-7-methoxy-N-methylisoquinoline-8-ol 

Relevant academic research and scientific papers

Synthetic Approaches To Cularines. II . Ullmann Condensation.

The first total syntheses of O-methylcularicine 9b and sarcocapnine 9c are described together with a new synthesis of cularine 9a using the Ullmann condensation reaction of the appropriate 2'-bromo-8-hydroxytetrahydrobenzylisoquinoline formed by phase-tra

ELECTROREDUCTIVE SYNTHESIS OF 1-(BROMOBENZYL)-ISOQUINOLINE DERIVATIVES AND ITS APPLICATION TO CULARINE SYNTHESIS

Electrochemical reduction of immonium salts in the presence of bromobenzylbromide derivatives gave 1-(bromobenzyl)-isoquinoline derivatives in moderate yields.This reaction is useful in the synthesis of several natural alkaloids as exemplified in the synt