78950-21-7Relevant articles and documents
Ferric chloride, an anomerization catalyst for the preparation of alkyl α-glycopyranosides
Ikemoto, Norihiro,Kim, Oak Kyung,Lo, Lee-Chiang,Satyanarayana, Vunnam,Chang, Mayland,Nakanishi, Koji
, p. 4295 - 4298 (2007/10/02)
Anhydrous FeCl3 in CH2Cl2 has been found to readily anomerize β-glycopyranosides to their corresponding α-anomers in good yields and selectivities at room temperatures. Acetyl- and benzoyl-protected oxygen sugars yielded the best results.
CHARACTERIZATION OF METHYL GLYCOSIDES AT THE PICO- TO NANO-GRAM LEVEL
Golik, Jerzy,Liu, Hung-Wen,Dinovi, Michael,Furukawa, Jun,Nakanishi, Koji
, p. 135 - 146 (2007/10/02)
We describe a general method that permits characterization of 100-pg to 1-ng quantities of sugars.Thus, oligosaccharides are subjected to methanolysis, followed by per-p-bromobenzoylation or pernaphthoylation, and the methyl glycoside peresters are separated by high-pressure liquid chromatography.The method is also applicable to amino and acetamido sugars.If required, the separated sugar derivatives may be unequivocally identified by the characteristic quasi-M+ peaks of bromobenzoates and extrema of excitation-split circular-dichroism (c.d.) curves.Furthermore, as the c.d. extrema of polybenzoates are predictable from extrema of component dibenzoate units, the c.d. data yield information on the unknown spatial disposition of -OH, -NH2, and -NHAc groups of glycopyranoses.Application of the method is demonstrated with viridopentaose C, a pentasaccharide obtained from the antibiotic sporaviridin.
