78956-19-1Relevant academic research and scientific papers
Tandem alkylation-cyclization process via an O,C-dianion
Banaag, April R.,Berger, Gideon O.,Dhoro, Francis,Delos Santos, Derrick B.,Dixon, Darryl D.,Mitchell, James P.,Tokeshi, Bradley K.,Tius, Marcus A.
, p. 3419 - 3428 (2007/10/03)
A general protocol for preparing densely functionalized cyclopentenones through a tandem nucleophilic addition-deprotonation-alkylation-cyclization process is described. Addition of lithioallene 2 to enamides 1 generates tetrahedral intermediate 3. Deprotonation of the γ carbon atom of the allene function in situ, followed by trapping by a suitable electrophile and cyclization during workup leads to C6 substituted cyclopentenones 6.
On the Reaction of Diphenylcyclopropenone, its Functional Derivatives and Imonium Salts with Amines
Eicher, Theophil,Boehm, Siegfried,Ehrhardt, Heinz,Harth, Robert,Lerch, Dieter
, p. 765 - 788 (2007/10/02)
The reactions of cyclopropenones 1, 2, cyclopropenone imines 3 and cyclopropenone imonium cations 5 with amines of different type are investigated and the structure of the products obtained is elucidated by means of spectral data and chemical behavior.The possible reaction modes and mechanisms are discussed.
