78959-40-7

Basic information

• Product Name: tert-butyl 2-(2H-1,4-benzoxazin-3-yl)hydrazinecarboxylate
• CAS NO: 78959-40-7
• Molecular Formula: C₁₃H₁₇N₃O₃
• Molecular Weight: 263.2924
• Mol File: 78959-40-7.mol
• Article Data: 1

Chemical Properties

• Density: 1.24g/cm³
• Refractive Index: 1.575
• CAS DataBase Reference: tert-butyl 2-(2H-1,4-benzoxazin-3-yl)hydrazinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(2H-1,4-benzoxazin-3-yl)hydrazinecarboxylate(78959-40-7)
• EPA Substance Registry System: tert-butyl 2-(2H-1,4-benzoxazin-3-yl)hydrazinecarboxylate(78959-40-7)

Safety Data

• Hazardous Substances Data: 78959-40-7(Hazardous Substances Data)

Upstream product

• 21744-76-3 3-methylthio-2H-1,4-benzoxazine 
• 870-46-2 t-butoxycarbonylhydrazine 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 14183-51-8 2H-1,4-benzoxazin-3(4H)-thione 

Relevant articles and documents

Synthesis and Biological Activity of Some 2H-1,4-Benzothiazin-3-yl- and 2H-1,4-Benzoxazin-3-yl-hydrazides

A series of 2H-1,4-benzothiazin-3-yl- and 2H-1,4-benzoxazin-3-yl-hydrazides (IV-VI; 1-41) have been synthesised and subjected to a wide range of biological screening which includes antiinflammatory, antibacterial, antimycobacterial, antifungal and anthelmintic testing.In the preliminary screening, several compounds in this series are found to possess promising antiinflammatory activity against carrageenin-induced oedema in rats, 40 being the most active member of the series showing 53.21percent inhibition at 200 mg/kg (p.o.) dose.Compound 41 displays significant antitubercular activity in vitro against Mycobacterium tuberculosis H37Rv as well as against INH and streptomycin resistant strains 10(N)-1> of M. tuberculosis.None of the compounds shows any noteworthy antibacterial, antifungal and anthelmintic activities.