78972-83-5

Upstream product

• 78972-80-2 3-Chlor-5-dimethylamino-2-phenylhydrazonomethyl-4-aza-2,4-pentadiennitril 
• 5334-43-0 5-Amino-4-cyano-1-phenylpyrazole 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 100-63-0 phenylhydrazine 
• 52709-56-5 3-Chloro-5-dimethylamino-2-formyl-4-aza-2,4-pentadienenitrile 

Downstream Products

• 1315339-37-7 C₁₄H₈F₃N₇S 
• 1315339-39-9 C₁₉H₁₂FN₇S 
• 1315339-41-3 C₂₀H₁₂F₃N₇S 
• 1315339-40-2 C₁₉H₁₂FN₇S 
• 1315339-38-8 C₁₉H₁₂FN₇S 
• 21314-17-0 1-phenyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Microwave-assisted synthesis of some novel fluorinated pyrazolo[3,4-d] pyrimidine derivatives containing 1,3,4-thiadiazole as potential antitumor agents

A facile microwave-assisted procedure for synthesis of novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives containing 1,3,4-thiadiazole is described. This protocol presented such advantages as short reaction time, high yields, simple purification and

3-Chlor-5-dimethylamino-2-formyl-4-aza-2,4-pentadiennitril, Synthese und Umsetzungen mit Nucleophilen

3-Chloro-5-dimethylamino-2-formyl-4-aza-2,4-pentadienenitrile (7) is prepared by partial hydrolysis of the iminium perchlorate 1.In 7 the electrophilic centres (1, 3, 5) regioselectively react with secondary alkylamines, arylamines, and hydrazine derivatives to yield 3-amino-substituted formylazapentadienenitriles and (hydrazonomethyl)azapentadienenitriles.Intramolecular cyclisation leads to triazole betaines, pyrazoles, and 1,4-dihydropyrimidines.