78987-25-4Relevant academic research and scientific papers
Silver-Catalyzed para -Selective C-H Amination of 1-Naphthylamides with Azodicarboxylates at Room Temperature
Bai, He-Yuan,Ding, Tong-Mei,Hou, Si-Hua,Li, Quan-Zhe,Ma, Yan-Yan,Wang, Xun-Hui,Zhang, Shu-Yu,Zhao, Deng-Gao
supporting information, p. 2697 - 2704 (2019/06/19)
A simple and efficient protocol for para -selective C-H amination of 1-naphthylamide derivatives under silver catalysis is described. This reaction system could proceed without the help of directing group and a broad range of substrates were proved to be well tolerated. In addition, control experiments suggested that this reaction might not proceed via a single-electron-transfer process.
Lithiation of N-(2-Alkylphenyl)alkanamides and Related Compounds. A Modified Madelung Indole Synthesis
Houlihan, William J.,Parrino, Vincent A.,Uike, Yasuyuki
, p. 4511 - 4515 (2007/10/02)
A modified Madelung synthesis for the conversion of N-(alkylphenyl)alkanamides and related compounds to indoles, benzindoles, and azindoles has been developed.This procedure consists of treating the amide with 2 or 3 equiv of n-butyllithium or lithium diisopropylamide in tetrahydrofuran at temperatures from -20 to +25 deg C.Several examples where products other than indoles were formed from the starting amide are also reported.
