79000-43-4Relevant academic research and scientific papers
THE SYNTHESIS OF 9-(1-AZETIDINYL)-1,2,3,4-TETRAHYDROACRIDINE
Michalson, Eric T.,D'Andrea, Stan,Freeman, Jeremiah P.,Szmuszkovicz, Jacob
, p. 415 - 425 (2007/10/02)
Synthesis of analogue (2) of tacrine is described in which the primary amino group is replaced by the azetidine moiety.The synthesis was accomplished in two steps from the acridinone derivative 10.This involved conversion of 10 to triflate 11, followed by treatment with azetidine to give the target compound 2.
