79006-98-7Relevant academic research and scientific papers
Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147
Liu, Wei,Chan, Alice S. H.,Liu, Hongqiang,Cochrane, Stephen A.,Vederas, John C.
supporting information; experimental part, p. 14216 - 14219 (2011/11/05)
Lantibiotics are antimicrobial peptides produced by bacteria. Some are employed for food preservation, whereas others have therapeutic potential due to their activity against organisms resistant to current antibiotics. They are ribosomally synthesized and
N-Unsubstituted β-Lactams from β-Hydroxy-α-amino Acids. Facile Preparation of Intermediates for Isocephalosporins
Bose, Ajay K.,Manhas, M. S.,Vincent, J. E.,Gala, K.,Fernandez, I. F.
, p. 4075 - 4081 (2007/10/02)
A facile method has been devised for the synthesis of N-unsubstituted β-lactams.The cis-azido β-lactam (13) obtained by the reaction of azidoacetyl chloride and the Schiff base (10), derived from cinnamaldehyde and a threonine ester, is subjected to contr
