790224-67-8Relevant academic research and scientific papers
Synthesis characterization and cytotoxicity studies of platinum(II) complexes with reduced amino pyridine schiff base and its derivatives as ligands
Li, Li-Jun,Yan, Qin-Qin,Liu, Guo-Jun,Yuan, Zhen,Lv, Zhen-Hua,Fu, Bin,Han, Yan-Jun,Du, Jian-Long
, p. 1081 - 1089 (2017/05/29)
A series of reduced amino pyridine Schiff base platinum(II) complexes were prepared as potential anticancer drugs, and characterized by NMR, IR spectroscopy, elemental analysis, and molar conductivity. UV and CD results showed the binding mode between these compounds and salmon sperm DNA may be intercalation. The cytotoxicity of these complexes was validated against A549, Hela, and MCF-7 cell lines by MTT assay. Some complexes exhibited better cytotoxic activity than cisplatin against Hela and MCF-7 cell lines.
New dioxo-molybdenum(vi) and -tungsten(vi) complexes with N-capped tripodal N2O2 tetradentate ligands: Synthesis, structures and catalytic activities towards olefin epoxidation
Wong, Yee-Lok,Tong, Lok H.,Dilworth, Jonathan R.,Ng, Dennis K. P.,Lee, Hung Kay
experimental part, p. 4602 - 4611 (2010/08/22)
A series of N2O2 tripodal tetradentate ligands derived from di-/tetra-tert-butyl substituted 2-[bis(2-hydroxybenzyl) aminomethyl]X (X = pyridine and benzimidazole) (H2Ln (n = 1-4)) and 8-[bis(3,5-di-tert-butyl-2-hydroxybenzyl)]aminoquinoline (H 2L5) were synthesised through a 4-step reaction scheme involving sequential formylation, reduction, bromination and alkylation. Treatment of H2Ln (n = 1-5) with [WO2Cl 2(dme)] (dme = 1,2-dimethoxyethane) in the presence of triethylamine gave the corresponding cis-dioxotungsten(vi) complexes [WO2(L n)] (n = 1-5). The corresponding molybdenum analogues [MoO 2(Ln)] (n = 1-5) were also prepared from the reaction of [MoO2(acac)2] (acac = acetylacetonate) with H 2Ln (n = 1-3) or [MoO2Cl2(dme)] (dme = 1,2-dimethoxyethane) with H2Ln (n = 4 and 5). All these compounds were fully characterised by a wide range of spectroscopic methods. The molecular structures of [MoO2(Ln)] (n = 2, 4) and [WO2(L2)] were also confirmed by single-crystal X-ray diffraction analysis. The catalytic activities of [MO2(L n)] (M = Mo, W; n = 1-4) towards epoxidation of styrene were also examined.
Synthesis and characterisation of a high valent dinuclear Mn(III,III) complex of a triphenolate ligand [N4O3]3- with two extra functional groups
Li, Hongyang,Shi, Feng,Gao, Yan,Zhang, Rong,Peng, Xiaojun,Sun, Licheng
, p. 57 - 58 (2007/10/03)
A new high valent complex [Mn2(III,III)L(μ-OAc) 2]·PF6 7 was prepared, where L was the tri-anion of 2,6-Bis {[(2-hydroxy-5-tert-butylbenzyl)(pyridyl-2-methyl)amino]methyl}-4-methylphenol which contained two additional phenolate groups and two tert-butyl groups compared to its parent [Mn2(II,II)(bpmp)(μ-OAc) 2]·PF6. These improvements narrowed the disparity between the new model and (Mn)4 cluster (OEC in nature).
