79025-27-7

Upstream product

• 67-56-1 methanol 
• 5701-87-1 3,4-dimethoxyanthranilic acid 
• 79025-28-8 3,4-Dimethoxy-2-nitro-benzoic acid 
• 215648-57-0 3,4-dimethoxy-2-nitro-benzoic acid methyl ester 

Downstream Products

• 215648-30-9 methyl-2,2'-dithiobis<3,4>-dimethoxybenzoate 
• 1136-26-1 5-chloro-3,4-dimethoxyanthranilic acid 
• 13794-72-4 6,7-dimethoxy quinazolin-4-one 
• 90794-40-4 2-Jod-veratrumsaeure-methylester 

Relevant academic research and scientific papers

Endothelin receptor antagonists: Synthesis and structure-activity relationships of substituted benzothiazine-1,1-dioxides

The development of benzothiazine-1,1-dioxide derivatives as a new structural class of potent endothelin receptor antagonists is described. Structure-activity relationships (SAR) revealed that PD164800 (1) is a potent antagonist of the ET(A) receptor subtype. Copyright (C) 1998 Elsevier Science Ltd.

Alkoxy-substituted-6-chloro-quinazoline-2,4-diones

2,4-Diaminoquinazolines of the formula STR1 wherein Y1 is hydrogen or chloro, Y2 is OR, Y3 is hydrogen or OR such that when Y1 is hydrogen, Y3 is OR and when Y1 is chloro, Y3 is hydrogen or OR, and the pharmaceutically acceptable salts thereof; R represents an alkyl group having from one to three carbon atoms; taken separately, R1 and R2 are each hydrogen, alkyl having from one to five carbon atoms, cycloalkyl having from three to eight carbon atoms, alkenyl or alkynyl each having from three to five carbon atoms or hydroxy substituted alkyl having from two to five carbon atoms, when taken together with the nitrogen atom to which they are attached R1 and R2 form a substituted or unsubstituted heterocyclic group optionally containing an atom of oxygen, sulfur or a second atom of nitrogen as a ring member; their use as antihypertensive agents, pharmaceutical compositions containing them and intermediates for their production.