79051-08-4

Basic information

• Product Name: 2-(4-benzyl-1-piperazinyl)-5,6,7,8-tetrahydro-4(3H)-quinazolinone
• Synonyms: 2-(4-benzyl-1-piperazinyl)-5,6,7,8-tetrahydro-4(3H)-quinazolinone
• CAS NO: 79051-08-4
• Molecular Weight: 324.426
• Mol File: 79051-08-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-benzyl-1-piperazinyl)-5,6,7,8-tetrahydro-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-benzyl-1-piperazinyl)-5,6,7,8-tetrahydro-4(3H)-quinazolinone(79051-08-4)
• EPA Substance Registry System: 2-(4-benzyl-1-piperazinyl)-5,6,7,8-tetrahydro-4(3H)-quinazolinone(79051-08-4)

Safety Data

• Hazardous Substances Data: 79051-08-4(Hazardous Substances Data)

Upstream product

• 1127-86-2 4-amino-2-chloro-5,6,7,8-tetrahydroquinazoline 
• 77766-03-1 2-methylsulfanyl-5,6,7,8-tetrahydroquinazolin-4-ylamine 
• 108-94-1 cyclohexanone 
• 2759-28-6 1-phenylmethylpiperazine 
• 908010-10-6 2-(4-benzylpiperazin-1-yl)-6-(phenylsulfonyl)-5,6,7,8-tetrahydro-3H-quinazolin-4-one 
• 908009-83-6 2-methylthio-6-(phenylsulfonyl)-5,6,7,8-tetrahydro-3H-quinazolin-4-one 
• 908009-76-7 3-methylthio-2,4-diazabicylo[4.2.0]octa-1⁽⁶⁾,2-dien-5-one 
• 908010-22-0 2-(4-benzylpiperazin-1-yl)-7,8-dihydro-3H-quinazolin-4-one 
• 34170-21-3 2-methylsulfanyl-5.6.7.8-tetrahydro-3H-quinazolin-4-one 

Downstream Products

• 79051-10-8 2-(4-benzyl-1-piperazinyl)-4-chloro-5,6,7,8-tetrahydroquinazoline 

Relevant articles and documents

Access to variously substituted 5,6,7,8-tetrahydro-3H-quinazolin-4-ones via Diels-Alder adducts of phenyl vinyl sulfone to cyclobutene-annelated pyrimidinones

Under basic conditions (Et3N, dioxane), the aromatic amidines 4 and also S-methylisothiourea 4g cleanly undergo Michael addition to methyl 2-chloro-2-cyclopropylideneacetate (5), followed by intramolecular nucleophilic substitution, cyclopropyl