79069-22-0Relevant academic research and scientific papers
Enantioselective dioxytosylation of styrenes using lactate-based chiral hypervalent iodine(III)
Fujita, Morifumi,Miura, Koki,Sugimura, Takashi
, p. 659 - 663 (2018)
A series of optically active hypervalent iodine(III) reagents prepared from the corresponding (R)-2-(2-iodophenoxy)propanoate derivative was employed for the asymmetric dioxytosylation of styrene and its derivatives. The electrophilic addition of the hype
Solvent-free reactions with hypervalent iodine reagents
Yusubov, Mekhman S.,Wirth, Thomas
, p. 519 - 521 (2007/10/03)
(Chemical Equation Presented) We describe solvent-free reactions for the synthesis of hypervalent iodine reagents and their use in solid-state reactions. Improved yields and higher purities of the products are observed.
New chiral hypervalent iodine compounds in asymmetric synthesis
Hirt, Urs H.,Spingler, Bernhard,Wirth, Thomas
, p. 7674 - 7679 (2007/10/03)
The synthesis of new chiral hypervalent iodine compounds 3 and their use in asymmetric oxidative functionalizations are described. The substituents in the chiral moiety and the stereoelectronic properties of the reagents 3, as well as the reaction conditions, have been optimized. Chiral hypervalent iodine compounds 3 have been investigated in the asymmetric dioxytosylation of styrène and in the a-oxytosylation of propiophenone as test reactions. X-ray structural analysis of some reagents shows an interaction between the chiral moiety and the iodine resulting in stereoselectivities up to 53% ee in the products.
