79090-91-8Relevant academic research and scientific papers
Solvent-Controlled Addition of Alkynyltins or Allylic Tins to Aldehydes Catalyzed by Indium Trichloride
Yasuda, Makoto,Miyai, Takashi,Shibata, Ikuya,Baba, Akio,Nomura, Ryoki,Matsuda, Haruo
, p. 9497 - 9500 (1995)
Indium trichloride promoted catalytically the addition of alkynyltins or allylic tins to aldehydes in two ways: transmetallation with the tin compounds and activation of aldehydes as a Lewis acid.The stereochemical outcome in the addition of cinnamylbutyl
REACTIVITE DES DERIVES ORGANOCUIVREUX VIS-A-VIS DES ALDEHYDES αβ-ETHYLENIQUES
Chuit, C.,Foulon, J. P.,Normant, J. F.
, p. 1385 - 1389 (2007/10/02)
Secondary lithium dialkylcuprates react with αβ-ethylenic aldehydes to give a mixture of 1,2 and 1,4 addition products.Only 1,2 addition products are obtained with allylic and acetylenic cuprates whereas homallylic, phenyl and vinylic cuprates give 1,4 addition products.The 1,4/1,2 ratio also depends on the nature of the metal in the cuprate (Mg or Li).Thus chloromagnesium dimethyl cuprate, in THF, is the most favorable compound to give the 1,4 addition product.
