79095-51-5Relevant academic research and scientific papers
The proposed structures of phenolic compounds isolated from Piper betle L. differ from those of the compounds obtained by total synthesis
Noshita, Toshiro,Sato, Tatsuya,Iwayama, Takahito,Yamada, Yohei,Ouchi, Hidekazu
, p. 3787 - 3793 (2021)
We describe the syntheses of phenolic compounds, 4-[(1E, 3E, 5E)?6-(4-octyloxyphenyl)hexa-1,3,5-trien-1-yl]benzene-1,2-diol (1) and 3-(n-dodecyloxy) phenol (2), isolated from Piper betle. The triene moiety of 4-[(1E, 3E, 5E)?6-(4-octyloxyphenyl)hexa-1,3,5
Polarization effect in luminescent mesogenic BF2 complexes derived from heterocyclic benzothiazoles
Hsu, Yuan?Chun,Wang, Chun?Yang,Hsiao, Pei?Chi,Cai, Yi-Hong,Lee, Gene?Hsiang,Lai, Chung K.
, (2019/12/09)
Two series of benzo(thia)xazoles 1–2 and one series of boron difluoride complexes 2-BF2 derived from benzothiazoles 2 were reported, and their mesomorphic and optical properties were investigated. The crystal and molecular structures of compound 2 and 2-BF2 (all n = 8) were determined by means of X?ray structural analysis, and both crystallize in the triclinic P-1 and monoclinic P21/c. The geometry at boron center is perfectly tetrahedral, and the overall molecular shapes are considered as rod?shape. Both benzo(thia)xazoles 1 and 2 exhibited N or/and SmC phase, and boron complexes 2-BF2 formed N or/and SmC phase. Benzothiazoles 2 showed a much wider temperature range of mesophase than those of benzoxazoles 1, which were attributed to the better polarization by sulfur atom incorporated. Boron complexes 2-BF2 (n = 10, 12) emitted a yellow?to?green emission at λmax = 569–571 nm in CH2Cl2. This is the first mesogenic BF2 complexes derived from benzothiazoles.
Mesogenic heterocycles derived from quinoxaline Schiff Bases
Kuo, Hsiu-Ming,Ko, Wan-Ping,Hsu, Yu-Te,Lee, Gene-Hsiang,Lai, Chung K.
, p. 6321 - 6333 (2016/09/23)
Three new series of heterocyclic quinoxaline Schiff Bases 1–2 were prepared, characterized and their mesomorphic properties were investigated. These compounds 1 and 2 are in fact geometric isomers in which an imine moiety (e.g., [sbnd]C[dbnd]N) is inversely incorporated into quinoxaline, leading to an opposite local dipole. Two single crystallographic structures 1 (m=8, n=8) and 2a (m=12, n=8) were determined by X-ray crystallographic analysis in order to understand the effect of mesomorphic properties. Weak H-bonds, CH–π and π–π interactions were found in both crystals, which were attributed to the formation of mesomorphic behavior. Variable temperature FT-IR experiments were performed to confirm the induced H-bonds. All series?of compounds 1–2 exhibited N/SmC or SmC phases, which were identified by optical microscope and confirmed by powder X-ray diffraction experiments. Compounds 2a have a slightly wider range of mesophase temperatures than that of compounds 1 and 2b.
Catenar bimetallomesogens derived from quinoxaline-salicylaldimine conjugates
Chu, Yian-Yuan,Kuo, Hsiu-Ming,Wu, Yu-Che,Wu, Chin-Yi,Sheu, Hwo-Shuenn,Lee, Gene-Hsiang,Chen, Ming-Chou,Lai, Chung K.
, p. 2389 - 2399 (2014/04/03)
The preparation, characterization, and mesomorphic properties of two series of tridentate N-salicylidene-2-hydroxyanilines and their metal complexes were described. The crystal and molecular structure of bis[2-hydroxy-4-propyloxy-N- (2-hydroxy-3,4-dipropy
Discotic liquid crystals of transition metal complexes 45?: Parity effect of the number of d-electrons on stacking distances in the columnar mesophases of octakis-(M-alkoxyphenoxy)phthalocyaninato metal(II) complexes
Sato, Hiroyuki,Igarashi, Kensaku,Yama, Yoshitaka,Ichihara, Masahiro,Itoh, Eiji,Ohta, Kazuchika
, p. 1148 - 1158 (2013/01/15)
We have synthesized 34 novel homologous discotic liquid crystals, octakis(m-alkoxyphenoxy)phthalocyaninato metal(II) {abbreviated as (m-C nOPhO)8PcM (M = Co(1), Ni(2), Cu(3), Zn(4) and H 2(5); n = 8(a), 10(b), 12(c), 14(d)
Columnar/smectic metallomesogens derived from heterocyclic benzoxazoles
Wu, I-Tzu,Chaing, Pei-Yi,Chang, Wen-Jung,Sheu, Hwo-Shuenn,Lee, Gene-Hsiang,Lai, Chung K.
scheme or table, p. 7358 - 7369 (2011/10/12)
The synthesis, mesomorphic behavior, and optical properties of two new series of metal complexes 1a,b-M (M=Pd, Cu, Zn) derived from benzoxazoles 2a,b are reported. The crystal and molecular structures of mesogenic 5-decyloxy-2-(6-decyloxybenzooxazol-2-yl)
The effect of polar substituents on the heterocyclic benzoxazoles
Wang, Chung-Shu,Wang, I-Wen,Cheng, Kung-Lung,Lai, Chung K.
, p. 9383 - 9392 (2007/10/03)
The synthesis, characterization, and mesomorphic properties of a new type of heterocyclic compounds 1, 2 derived from benzoxazole are reported. In order to understand the relationship between the structure and the mesomorphic behavior, compounds containin
2-(Dialkylamino)-4H-1-benzopyran-4-one derivatives modify chloride conductance in CFTR expressing cells
Mazzei, Mauro,Nieddu, Erika,Folli, Chiara,Caci, Emanuela,Galietta, Louis V.J.
, p. 961 - 970 (2007/10/03)
Some 2-(diethylamino)-7-hydroxy-4H-1-benzopyran-4-one derivatives, potentially useful as activators of the cystic fibrosis transmembrane conductance regulator (CFTR), were prepared. The synthesized compounds were tested, together with others 2-(dialkylami
Analogues of Platelet Activating Factor. 6. Mono- and Bis-Aryl Phosphate Antagonists of Platelet Activating Factor
Wissner, A.,Carroll, M. L.,Green, K. E.,Kerwar, S. S.,Pickett, W. C.,et al.
, p. 1650 - 1662 (2007/10/02)
A series of aryl phosphoglyceride (3, 19-61) and bis-aryl phosphate (67-135) antagonists of platelet activating factor (PAF) were prepared.A group of four bifunctional phosphorus reagents (5a-c and 7) were developed that allowed the preparation of these aryl phosphates in which the position of aromatic substitution can be varied.These compounds were examined for their ability to inhibit PAF-induced platelet aggregation of rabbit platelets.Selected compounds were also evaluated for their ability to displace PAF from its receptor on rabbit platelets.These in vitro data were compared to similar data obtained for a number of known PAF antagonists.The compounds were evaluated in vivo, in both the mouse and rabbit, for their ability to prevent death induced by a lethal challenge of PAF.The relationships between the biological activity and the nature, lipophilicity, and position of substituents of the aromatic rings were studied.Compound 105 (CL 184005) has been selected to undergo further development as a potential therapeutic agent for the treatment of septic shock in man.
Bis-arylphosphate ester antagonists of platelet activating factor
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, (2008/06/13)
The invention is novel compounds of the formula: STR1 which are antagonists of platelet activating factor.
