791-37-7Relevant articles and documents
Tuning the reducing properties of 1,2-diaryl-1,2-disodiumethanes
Azzena, Ugo,Pisano, Luisa,Antonello, Sabrina,Maran, Flavio
supporting information; experimental part, p. 8064 - 8070 (2010/03/02)
(Chemical Equation Presented) We investigated the reducing properties of a series of 1,2-diaryl-1,2-disodiumethanes by means of equilibration reactions. The electron-donor power of these vic-diorganometals is strongly affected by the nature of substituents present either on the aromatic ring(s) or on the carbanionic centers, and it can be correlated with their ability to delocalize the arylmethyl carbanions. These findings are supported by electrochemical analysis of the reduction behavior of the parent 1,2-diarylalkene. Applications of these results to the reduction of selected substrates are described. 2009 American Chemical Society.
NOVEL TRICYCLIC, BICYCLIC, MONOCYCLIC, AND ACYCLIC AMINES AS POTENT SODIUM CHANNEL BLOCKING AGENTS
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Page/Page column 37, (2008/06/13)
The present invention provides acyclic, bicyclic, monocyclic, and tricyclic analogs and derivatives of tricyclic antidepressants which have sodium channel inhibiting activity. The compounds of the invention are useful as analgesics and anesthetics for diseases, conditions, and disorders where regulation of sodium channel activity can alleviate pain.
ONE-STEP GRIGNARD REACTIONS WITH DIMETHYLAMINOPROPYL CHLORIDE: APPLICATION TO THE SYNTHESIS OF TRICYCLIC DRUGS
Miodownik, A.,Kreisberger, J.,Nussim, M.,Avnir, D.
, p. 241 - 246 (2007/10/02)
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